The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana

Nelly J. Yatich, Pauline E. Jolly, Ellen Funkhouser, Tsiri Agbenyega, Julian C. Rayner, John E Ehiri, Archer Turpin, Jonathan K. Stiles, William O. Ellis, Yi Jiang, Jonathan H. Williams

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

This study was conducted to investigate the effect of Plasmodium falciparum and intestinal helminth coinfection on maternal anemia and birth outcomes. A cross-sectional study of 746 women who delivered in two hospitals in Kumasi was conducted. Data were collected using an investigator-administered questionnaire and from patients' medical records. Blood was collected for determination of P. falciparum and hemoglobin levels. Adverse pregnancy outcomes were high (44.6%). Coinfection (versus no infection) was associated with 3-fold increase in low birth weight. For women with anemia, coinfection was 2.6 times and 3.5 times as likely to result in preterm deliveries and small for gestational age infants. The odds of having anemia was increased almost 3-fold by coinfection. Coinfection (versus helminth only) resulted in increased risks of anemia, low birth weight, and small for gestational age infants. This study demonstrates that women with malaria and intestinal helminth coinfection are at particular risk of adverse birth outcomes.

Original languageEnglish (US)
Pages (from-to)28-34
Number of pages7
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume82
Issue number1
DOIs
StatePublished - Jan 2010
Externally publishedYes

Fingerprint

Ghana
Helminths
Coinfection
Malaria
Parturition
Anemia
Small for Gestational Age Infant
Low Birth Weight Infant
Plasmodium falciparum
Pregnancy Outcome
Medical Records
Hemoglobins
Cross-Sectional Studies
Mothers
Research Personnel
Infection

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana. / Yatich, Nelly J.; Jolly, Pauline E.; Funkhouser, Ellen; Agbenyega, Tsiri; Rayner, Julian C.; Ehiri, John E; Turpin, Archer; Stiles, Jonathan K.; Ellis, William O.; Jiang, Yi; Williams, Jonathan H.

In: American Journal of Tropical Medicine and Hygiene, Vol. 82, No. 1, 01.2010, p. 28-34.

Research output: Contribution to journalArticle

Yatich, NJ, Jolly, PE, Funkhouser, E, Agbenyega, T, Rayner, JC, Ehiri, JE, Turpin, A, Stiles, JK, Ellis, WO, Jiang, Y & Williams, JH 2010, 'The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana', American Journal of Tropical Medicine and Hygiene, vol. 82, no. 1, pp. 28-34. https://doi.org/10.4269/ajtmh.2010.09-0165
Yatich, Nelly J. ; Jolly, Pauline E. ; Funkhouser, Ellen ; Agbenyega, Tsiri ; Rayner, Julian C. ; Ehiri, John E ; Turpin, Archer ; Stiles, Jonathan K. ; Ellis, William O. ; Jiang, Yi ; Williams, Jonathan H. / The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana. In: American Journal of Tropical Medicine and Hygiene. 2010 ; Vol. 82, No. 1. pp. 28-34.
@article{56efc39f4ec547f598a001ffa115d0fc,
title = "The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana",
abstract = "This study was conducted to investigate the effect of Plasmodium falciparum and intestinal helminth coinfection on maternal anemia and birth outcomes. A cross-sectional study of 746 women who delivered in two hospitals in Kumasi was conducted. Data were collected using an investigator-administered questionnaire and from patients' medical records. Blood was collected for determination of P. falciparum and hemoglobin levels. Adverse pregnancy outcomes were high (44.6{\%}). Coinfection (versus no infection) was associated with 3-fold increase in low birth weight. For women with anemia, coinfection was 2.6 times and 3.5 times as likely to result in preterm deliveries and small for gestational age infants. The odds of having anemia was increased almost 3-fold by coinfection. Coinfection (versus helminth only) resulted in increased risks of anemia, low birth weight, and small for gestational age infants. This study demonstrates that women with malaria and intestinal helminth coinfection are at particular risk of adverse birth outcomes.",
author = "Yatich, {Nelly J.} and Jolly, {Pauline E.} and Ellen Funkhouser and Tsiri Agbenyega and Rayner, {Julian C.} and Ehiri, {John E} and Archer Turpin and Stiles, {Jonathan K.} and Ellis, {William O.} and Yi Jiang and Williams, {Jonathan H.}",
year = "2010",
month = "1",
doi = "10.4269/ajtmh.2010.09-0165",
language = "English (US)",
volume = "82",
pages = "28--34",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "1",

}

TY - JOUR

T1 - The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana

AU - Yatich, Nelly J.

AU - Jolly, Pauline E.

AU - Funkhouser, Ellen

AU - Agbenyega, Tsiri

AU - Rayner, Julian C.

AU - Ehiri, John E

AU - Turpin, Archer

AU - Stiles, Jonathan K.

AU - Ellis, William O.

AU - Jiang, Yi

AU - Williams, Jonathan H.

PY - 2010/1

Y1 - 2010/1

N2 - This study was conducted to investigate the effect of Plasmodium falciparum and intestinal helminth coinfection on maternal anemia and birth outcomes. A cross-sectional study of 746 women who delivered in two hospitals in Kumasi was conducted. Data were collected using an investigator-administered questionnaire and from patients' medical records. Blood was collected for determination of P. falciparum and hemoglobin levels. Adverse pregnancy outcomes were high (44.6%). Coinfection (versus no infection) was associated with 3-fold increase in low birth weight. For women with anemia, coinfection was 2.6 times and 3.5 times as likely to result in preterm deliveries and small for gestational age infants. The odds of having anemia was increased almost 3-fold by coinfection. Coinfection (versus helminth only) resulted in increased risks of anemia, low birth weight, and small for gestational age infants. This study demonstrates that women with malaria and intestinal helminth coinfection are at particular risk of adverse birth outcomes.

AB - This study was conducted to investigate the effect of Plasmodium falciparum and intestinal helminth coinfection on maternal anemia and birth outcomes. A cross-sectional study of 746 women who delivered in two hospitals in Kumasi was conducted. Data were collected using an investigator-administered questionnaire and from patients' medical records. Blood was collected for determination of P. falciparum and hemoglobin levels. Adverse pregnancy outcomes were high (44.6%). Coinfection (versus no infection) was associated with 3-fold increase in low birth weight. For women with anemia, coinfection was 2.6 times and 3.5 times as likely to result in preterm deliveries and small for gestational age infants. The odds of having anemia was increased almost 3-fold by coinfection. Coinfection (versus helminth only) resulted in increased risks of anemia, low birth weight, and small for gestational age infants. This study demonstrates that women with malaria and intestinal helminth coinfection are at particular risk of adverse birth outcomes.

UR - http://www.scopus.com/inward/record.url?scp=74049159927&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74049159927&partnerID=8YFLogxK

U2 - 10.4269/ajtmh.2010.09-0165

DO - 10.4269/ajtmh.2010.09-0165

M3 - Article

VL - 82

SP - 28

EP - 34

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 1

ER -