The effect of post-conditioning exposure to morphine on the retention of a morphine-induced conditioned taste aversion

William J Jacobs, D. A. Zellner, V. M. LoLordo, A. L. Riley

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In the following experiment, multiple injections of morphine sulfate following the acquisition of a morphine-induced taste aversion had no effect on the retention of the previously acquired aversion. Post-conditioning injections of morphine resulted in the development of physical dependence to morphine and led to a decrement in the ability of morphine to induce a subsequent aversion to a second novel taste. This failure of post-conditioning exposures to morphine to affect a previously acquired morphine-induced taste aversion even though tolerance to morphine had occured was discussed in the context of Rescorla's event-memory model of conditioning.

Original languageEnglish (US)
Pages (from-to)779-785
Number of pages7
JournalPharmacology, Biochemistry and Behavior
Volume14
Issue number6
DOIs
StatePublished - 1981
Externally publishedYes

Fingerprint

Morphine
Morphine Dependence
Injections
Aptitude
Conditioning (Psychology)
Retention (Psychology)
Data storage equipment
Experiments

Keywords

  • Blocking
  • Conditioned taste aversion
  • Dependence
  • Morphine
  • Naloxone
  • Tolerance
  • UCS habituation
  • UCS pre-exposure

ASJC Scopus subject areas

  • Biochemistry
  • Behavioral Neuroscience
  • Pharmacology

Cite this

The effect of post-conditioning exposure to morphine on the retention of a morphine-induced conditioned taste aversion. / Jacobs, William J; Zellner, D. A.; LoLordo, V. M.; Riley, A. L.

In: Pharmacology, Biochemistry and Behavior, Vol. 14, No. 6, 1981, p. 779-785.

Research output: Contribution to journalArticle

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