The hemostatic history of a 15-month-old child implanted with a Berlin Heart left ventricular assist device

Brad L. Steenwyk, James K. Kirklin, William Q. Gurley, Vance G Nielsen

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We documented the hemostatic changes associated with placement of a EXCOR® Berlin Heart left ventricular assist device in a 15-month-old child before heart transplantation. The development of hypercoagulability was rapid, manifested first by a plasmatic and subsequently platelet-mediated increase in coagulation kinetics and strength that persisted for weeks. The patient had no thrombotic complications for 6 wk before transplant but required extraordinary blood product administration to achieve hemostasis secondary to aggressive, multimodal anticoagulation. In summary, when proscribing anesthetic and surgical management of patients with a Berlin Heart, consideration of hypercoagulable features and anticoagulant therapy must be made to maximize patient safety.

Original languageEnglish (US)
Pages (from-to)538-540
Number of pages3
JournalAnesthesia and Analgesia
Volume104
Issue number3
DOIs
StatePublished - Mar 2007
Externally publishedYes

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Heart-Assist Devices
Berlin
Hemostatics
History
Thrombophilia
Heart Transplantation
Patient Safety
Hemostasis
Anticoagulants
Anesthetics
Blood Platelets
Transplants
Therapeutics

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

The hemostatic history of a 15-month-old child implanted with a Berlin Heart left ventricular assist device. / Steenwyk, Brad L.; Kirklin, James K.; Gurley, William Q.; Nielsen, Vance G.

In: Anesthesia and Analgesia, Vol. 104, No. 3, 03.2007, p. 538-540.

Research output: Contribution to journalArticle

Steenwyk, Brad L. ; Kirklin, James K. ; Gurley, William Q. ; Nielsen, Vance G. / The hemostatic history of a 15-month-old child implanted with a Berlin Heart left ventricular assist device. In: Anesthesia and Analgesia. 2007 ; Vol. 104, No. 3. pp. 538-540.
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