The Long Neglected Cycloidal Mass Analyzer

Elettra L. Piacentino, Rafael Bento Serpa, Kathleen L. Horvath, Raul Vyas, Tanouir Aloui, Charles B. Parker, James B. Carlson, Justin Keogh, Roger P. Sperline, Maria L. Sartorelli, Brian R. Stoner, Michael E. Gehm, Jeffrey T. Glass, M. Bonner Denton, Jason J. Amsden

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

In 1938, Walker Bleakney and John A. Hipple first described the cycloidal mass analyzer as the only mass analyzer configuration capable of "perfect"ion focusing. Why has their geometry been largely neglected for many years and how might it earn a respectable place in the world of modern chemical analysis? This Perspective explores the properties of the cycloidal mass analyzer and identifies the lack of suitable ion array detectors as a significant reason why cycloidal mass analyzers are not widely used. The recent development of capacitive transimpedance amplifier array detectors can enable several techniques using cycloidal mass analyzers including spatially coded apertures and single particle mass analysis with a "virtual-slit", helping the cycloidal mass analyzer earn a respectable place in chemical analysis.

Original languageEnglish (US)
Pages (from-to)11357-11363
Number of pages7
JournalAnalytical Chemistry
Volume93
Issue number33
DOIs
StatePublished - Aug 24 2021

ASJC Scopus subject areas

  • Analytical Chemistry

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