The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Neil M. Ampel, Daniel K. Nelson, Lijin Li, Sara O. Dionne, Douglas F. Lake, Keira A. Simmons, Demosthenes Pappagianis

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

Original languageEnglish (US)
Pages (from-to)2554-2555
Number of pages2
JournalInfection and Immunity
Volume73
Issue number4
DOIs
StatePublished - Apr 2005

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Coccidioidomycosis
Cellular Immunity
Interleukin-2
Mannans
Monosaccharides
Mannose
Anti-Idiotypic Antibodies
Blood Cells
Antigens
mannose receptor

ASJC Scopus subject areas

  • Immunology

Cite this

Ampel, N. M., Nelson, D. K., Li, L., Dionne, S. O., Lake, D. F., Simmons, K. A., & Pappagianis, D. (2005). The mannose receptor mediates the cellular immune response in human coccidioidomycosis. Infection and Immunity, 73(4), 2554-2555. https://doi.org/10.1128/IAI.73.4.2554-2555.2005

The mannose receptor mediates the cellular immune response in human coccidioidomycosis. / Ampel, Neil M.; Nelson, Daniel K.; Li, Lijin; Dionne, Sara O.; Lake, Douglas F.; Simmons, Keira A.; Pappagianis, Demosthenes.

In: Infection and Immunity, Vol. 73, No. 4, 04.2005, p. 2554-2555.

Research output: Contribution to journalArticle

Ampel, NM, Nelson, DK, Li, L, Dionne, SO, Lake, DF, Simmons, KA & Pappagianis, D 2005, 'The mannose receptor mediates the cellular immune response in human coccidioidomycosis', Infection and Immunity, vol. 73, no. 4, pp. 2554-2555. https://doi.org/10.1128/IAI.73.4.2554-2555.2005
Ampel, Neil M. ; Nelson, Daniel K. ; Li, Lijin ; Dionne, Sara O. ; Lake, Douglas F. ; Simmons, Keira A. ; Pappagianis, Demosthenes. / The mannose receptor mediates the cellular immune response in human coccidioidomycosis. In: Infection and Immunity. 2005 ; Vol. 73, No. 4. pp. 2554-2555.
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