The meddling microbes midst our medicines.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

It is not surprising that the complex metabolic machinery of the gut microbiome has accidental, or directed, ability to alter our medicines and influence their efficacy. What is not known is the extent to which this has contributed to drug failures or contraindications, or to the derailment of clinical trials. Some studies are unraveling the mechanisms by which the microbiota alter specific drugs, such as digoxin, and contribute to variations in efficacies between patient populations. Microbiome profiling, therefore, may well become an inevitable arm of all clinical trials in the future.

Original languageEnglish (US)
Pages (from-to)359-360
Number of pages2
JournalGut Microbes
Volume4
Issue number5
DOIs
StatePublished - 2013

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Microbiota
Clinical Trials
Digoxin
Pharmaceutical Preparations
Population
Gastrointestinal Microbiome

ASJC Scopus subject areas

  • Gastroenterology
  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology

Cite this

The meddling microbes midst our medicines. / Viswanathan, Virinchipuram.

In: Gut Microbes, Vol. 4, No. 5, 2013, p. 359-360.

Research output: Contribution to journalArticle

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