The michael addition of sulfur anions to β,β-substituted Nα-formyl-α,β-dehydroamino acid esters

C. Freeman Stanfield, Victor J. Hruby

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The addition of lithium benzylthiolates to Nα-formyl-α,β-dehydro-α-amino acid esters gave protected Nα-formyl-β-S-benzyl-β,S-dialkyl- cysteine esters. Hydrolysis and Nα-protection produced β,β-dialkyl-cysteines which can be used for peptide synthesis.

Original languageEnglish (US)
Pages (from-to)531-543
Number of pages13
JournalSynthetic Communications
Issue number5
StatePublished - Apr 1 1988

ASJC Scopus subject areas

  • Organic Chemistry


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