The motility of mollicutes

Charles W. Wolgemuth, Oleg Igoshin, George Oster

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Recent experiments show that the conformation of filament proteins play a role in the motility and morphology of many different types of bacteria. Conformational changes in the protein subunits may produce forces to drive propulsion and cell division. Here we present a molecular mechanism by which these forces can drive cell motion. Coupling of a biochemical cycle, such as ATP hydrolysis, to the dynamics of elastic filaments enable elastic filaments to propagate deformations that generate propulsive forces. We demonstrate this possibility for two classes of wall-less bacteria called mollicutes: the swimming of helical-shaped Spiroplasma, and the gliding motility of Mycoplasma.

Original languageEnglish (US)
Pages (from-to)828-842
Number of pages15
JournalBiophysical Journal
Volume85
Issue number2
DOIs
StatePublished - Aug 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics

Fingerprint Dive into the research topics of 'The motility of mollicutes'. Together they form a unique fingerprint.

  • Cite this