The motility of mollicutes

Charles William Wolgemuth, Oleg Igoshin, George Oster

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Recent experiments show that the conformation of filament proteins play a role in the motility and morphology of many different types of bacteria. Conformational changes in the protein subunits may produce forces to drive propulsion and cell division. Here we present a molecular mechanism by which these forces can drive cell motion. Coupling of a biochemical cycle, such as ATP hydrolysis, to the dynamics of elastic filaments enable elastic filaments to propagate deformations that generate propulsive forces. We demonstrate this possibility for two classes of wall-less bacteria called mollicutes: the swimming of helical-shaped Spiroplasma, and the gliding motility of Mycoplasma.

Original languageEnglish (US)
Pages (from-to)828-842
Number of pages15
JournalBiophysical Journal
Volume85
Issue number2
StatePublished - Aug 1 2003
Externally publishedYes

Fingerprint

Tenericutes
Spiroplasma
Bacteria
Protein Conformation
Mycoplasma
Protein Subunits
Cell Division
Hydrolysis
Adenosine Triphosphate

ASJC Scopus subject areas

  • Biophysics

Cite this

Wolgemuth, C. W., Igoshin, O., & Oster, G. (2003). The motility of mollicutes. Biophysical Journal, 85(2), 828-842.

The motility of mollicutes. / Wolgemuth, Charles William; Igoshin, Oleg; Oster, George.

In: Biophysical Journal, Vol. 85, No. 2, 01.08.2003, p. 828-842.

Research output: Contribution to journalArticle

Wolgemuth, CW, Igoshin, O & Oster, G 2003, 'The motility of mollicutes', Biophysical Journal, vol. 85, no. 2, pp. 828-842.
Wolgemuth CW, Igoshin O, Oster G. The motility of mollicutes. Biophysical Journal. 2003 Aug 1;85(2):828-842.
Wolgemuth, Charles William ; Igoshin, Oleg ; Oster, George. / The motility of mollicutes. In: Biophysical Journal. 2003 ; Vol. 85, No. 2. pp. 828-842.
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