The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum

M. Goedert, S. P. Hunt, P. W. Mantyh, P. C. Emson

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

At birth, striatal neurotensin-like immunoreactivity amounted to 10% of the adult values which were reached at the age of 5 weeks. In the caudate nucleus neurotensin-like immunoreactivity presented a patchy distribution throughout development that was in register with Met-enkephalin straining, whereas [3H]neurotensin binding sites were most heavily concentrated in the background matrix. Thus, the adult distribution pattern of neurotensin-like immunoreactivity and ]3H]neurotensin binding sites is already established at birth.

Original languageEnglish (US)
Pages (from-to)127-131
Number of pages5
JournalDevelopmental Brain Research
Volume20
Issue number1
DOIs
StatePublished - May 1985
Externally publishedYes

Keywords

  • development
  • neurotensin receptors
  • neurotensin-like immunoreactivity
  • striosomes

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

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