THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt, S. Wallace, E. J. Freireich, V. P. Chuang, E. M. Hersh, G. M. Mavligit

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

Original languageEnglish (US)
Pages (from-to)349-351
Number of pages3
JournalThe Lancet
Volume317
Issue number8216
DOIs
StatePublished - Feb 14 1981

ASJC Scopus subject areas

  • Medicine(all)

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