THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt, S. Wallace, E. J. Freireich, V. P. Chuang, Evan M Hersh, G. M. Mavligit

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Abstract

Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

Original languageEnglish (US)
Pages (from-to)349-351
Number of pages3
JournalThe Lancet
Volume317
Issue number8216
DOIs
Publication statusPublished - Feb 14 1981
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

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