The perfect storm: Torsades de Pointes in a child with leukemia

Rochelle Bagatell, Michael Hainstock, Merlin C. Lowe, Brent J. Barber, Ricardo A. Samson

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Torsades de Pointes (TdP) is a life-threatening ventricular arrhythmia that can be associated with metabolic abnormalities, exposure to arrhythmogenic medications, and congenital long-QT syndrome. This report describes a patient with ALL and multiple complications of therapy who developed TdP. The patient had no evidence of congenital long-QT syndrome, but a constellation of factors appears to have led to QT prolongation, ventricular ectopy, and TdP. Although the patient suffered cardiac arrest, rapid recognition of TdP and prompt defibrillation resulted in an excellent outcome.

Original languageEnglish (US)
Pages (from-to)996-999
Number of pages4
JournalPediatric Blood and Cancer
Volume49
Issue number7
DOIs
StatePublished - Dec 1 2007

Keywords

  • Acute lymphocytic leukemia
  • Cardiac arrest
  • Torsades de Pointes
  • Ventricular arrhythmia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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