The potential benefits of advanced therapeutic modalities in the treatment of diabetic foot wounds.

J. Hogge, D. Krasner, H. Nguyen, L. B. Harkless, D. G. Armstrong

Research output: Contribution to journalReview article

30 Scopus citations


This article discusses the advantages and disadvantages of primary wound healing as compared with primary amputation in individuals with chronic diabetic foot wounds. The authors review the potential benefits of vascular surgical procedures and advanced dressings, including two of the most promising modalities in modern wound care: growth factors and bioengineered skin. In this era of cost-conscious health-care administration, it is incumbent on the practitioner to consider not only the basic science of wound care, but also the economic aspect of treatment rendered. These various interventions, dressings, growth factor delivery systems, and new modalities could significantly reduce healing time, thereby reducing the risk of infection, hospitalization, and amputation while improving quality of life. If so, they may be truly cost-effective.

Original languageEnglish (US)
Pages (from-to)57-65
Number of pages9
JournalJournal of the American Podiatric Medical Association
Issue number2
StatePublished - Feb 2000


ASJC Scopus subject areas

  • Podiatry
  • Orthopedics and Sports Medicine

Cite this