The relationship between European genetic admixture and body composition among Hispanics and Native Americans

Yann C Klimentidis, G. F. Miller, M. D. Shriver

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Previous studies have shown a relationship between health-related phenotypes and the degree of African, European, or Native American genetic admixture, indicating that there may be a genetic component to these phenotypes. However, these relationships may be driven to a large extent by the environmental differences that co-vary with admixture differences between and within groups. In this study, we examine the relationship between genetic admixture and two phenotypic measurements that are potentially related to health: body mass index (BMI) and percent body fat (PBF). In addition to admixture proportions, we attempt to assess the influence of some environmental covariates by examining how the phenotypes vary with self-reported household income, education of parents, and physical activity level. Genetic, anthropometric, and environmental data were collected from 170 self-reported Hispanic and Native American university students in Albuquerque, NM. We examine the relationships between genetic admixture, phenotype, and environment in both the full sample, as well as in Hispanics and Native Americans separately. Among Hispanics, we find no significant relationship between genetic admixture and body composition. Among Native Americans, despite a small sample size, we find a statistically significant, negative relationship between European genetic admixture and PBF and BMI, after adjusting for other predictor variables. We compare our findings to previous research, and discuss their implications for understanding health disparities within and between ethnic groups.

Original languageEnglish (US)
Pages (from-to)377-382
Number of pages6
JournalAmerican Journal of Human Biology
Volume21
Issue number3
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

North American Indians
American Indians
Body Composition
Hispanic Americans
body composition
Phenotype
phenotype
Adipose Tissue
Health
Body Mass Index
Fat Body
body mass
body fat
fat
body mass index
Ethnic Groups
African Americans
Sample Size
parent education
health

ASJC Scopus subject areas

  • Anthropology
  • Anatomy
  • Genetics
  • Ecology, Evolution, Behavior and Systematics
  • Medicine(all)

Cite this

The relationship between European genetic admixture and body composition among Hispanics and Native Americans. / Klimentidis, Yann C; Miller, G. F.; Shriver, M. D.

In: American Journal of Human Biology, Vol. 21, No. 3, 2009, p. 377-382.

Research output: Contribution to journalArticle

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