The role of autophagy in salivary gland homeostasis and stress responses

M. Morgan-Bathke, H. H. Lin, D. K. Ann, Kirsten Limesand

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Autophagy is a catabolic process that has been shown to have a role in many cellular processes including the removal of excessive or damaged proteins and protein aggregates. The salivary glands play a critical role in oral health, and their secretory capacity may be critically intertwined with the autophagic process. This review describes the role of autophagy activation in normal salivary gland homeostasis and during the glandular stress responses of therapeutic radiation, ductal ligation, autoimmunity, and salivary gland adenoid cystic carcinoma.

Original languageEnglish (US)
Pages (from-to)1035-1040
Number of pages6
JournalJournal of Dental Research
Volume94
Issue number8
DOIs
StatePublished - Aug 25 2015

Fingerprint

Autophagy
Salivary Glands
Homeostasis
Adenoid Cystic Carcinoma
Oral Health
Autoimmunity
Ligation
Radiation
Proteins
Therapeutics

Keywords

  • cancer
  • ductal ligation
  • radiation
  • rapalogues
  • salivary physiology
  • Sjogren's syndrome

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

The role of autophagy in salivary gland homeostasis and stress responses. / Morgan-Bathke, M.; Lin, H. H.; Ann, D. K.; Limesand, Kirsten.

In: Journal of Dental Research, Vol. 94, No. 8, 25.08.2015, p. 1035-1040.

Research output: Contribution to journalArticle

Morgan-Bathke, M. ; Lin, H. H. ; Ann, D. K. ; Limesand, Kirsten. / The role of autophagy in salivary gland homeostasis and stress responses. In: Journal of Dental Research. 2015 ; Vol. 94, No. 8. pp. 1035-1040.
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