In these experiments, it was found that anoxia could abolish (reversibly) the generator potential of Limulus ventral photoreceptors in the absence of extracellular calcium. When the photoreceptors were poisoned with the metabolic inhibitor DNP, which has similar effects to anoxia, it was found that intracellular injection of the calcium chelator EGTA could restore the amplitude of the generator potential. Anoxia and DNP may exert their effects by raising the intracellular calcium ion concentration.
ASJC Scopus subject areas
- Sensory Systems