The role of calcium ions in the suppression of the photoresponse during anoxia and application of metabolic inhibitors

Fulton Wong, R. Clark Lantz, Alexander Mauro

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

In these experiments, it was found that anoxia could abolish (reversibly) the generator potential of Limulus ventral photoreceptors in the absence of extracellular calcium. When the photoreceptors were poisoned with the metabolic inhibitor DNP, which has similar effects to anoxia, it was found that intracellular injection of the calcium chelator EGTA could restore the amplitude of the generator potential. Anoxia and DNP may exert their effects by raising the intracellular calcium ion concentration.

Original languageEnglish (US)
Pages (from-to)251-254
Number of pages4
JournalVision Research
Volume19
Issue number3
DOIs
StatePublished - 1979
Externally publishedYes

Keywords

  • Ca
  • DNP
  • anoxia
  • photoreceptors

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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