The role of IgE in childhood asthma

R. Ronchetti, F. Martinez, P. Falagiani, F. Macrì, S. Criscione, G. M. Tramutoli, C. Imperato

Research output: Contribution to journalArticle

1 Scopus citations


The influence of age and sex has been evaluated in 208 asthmatic children on the basis of the following parameters: total serum IgE concentration (RIST), serum concentration of specific IgE antibodies (RAST), and positive prick tests against Dermathophagoides Pteronissinus, grasses, and Alternaria Tenuis. The results indicate that all these parameters are significantly influenced by age. Arithmetic values for RIST show a significant difference between the sexes which is obscured by logarithmic calculation. The data strongly suggest that IgE antibodies cannot be considered the main mechanism by which asthma is produced in small children.

Original languageEnglish (US)
Pages (from-to)36-40
Number of pages5
JournalInternational Journal of Clinical Pharmacology Therapy and Toxicology
Issue number1
StatePublished - Mar 20 1981
Externally publishedYes

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)

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  • Cite this

    Ronchetti, R., Martinez, F., Falagiani, P., Macrì, F., Criscione, S., Tramutoli, G. M., & Imperato, C. (1981). The role of IgE in childhood asthma. International Journal of Clinical Pharmacology Therapy and Toxicology, 19(1), 36-40.