Problems inherent in traditional methods of determining the hemolytic activity of parenteral compounds are discussed. Data taken from a study which closely models the conditions present for an intravenous injection are re- examined. An equation is given which combines several variables into a single parameter, the effective concentration. A strong relationship is found between the effective concentration of the compound of interest and the hemolysis produced.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of Parenteral Science and Technology|
|State||Published - Jan 1 1992|
ASJC Scopus subject areas
- Pharmaceutical Science