The role of the interhemispheric pathway in hearing

Doris Eva Bamiou, Sanjay Sisodiya, Frank E. Musiek, Linda M. Luxon

Research output: Contribution to journalReview articlepeer-review

48 Scopus citations

Abstract

The corpus callosum consists of heavily myelinated fibres connecting the two hemispheres. Its caudal portion and splenium contain fibres that originate from the primary and second auditory cortices, and from other auditory responsive areas. The anterior commissure in humans is much smaller than the corpus callosum, and it also contains interhemispheric fibres from auditory responsive cortical areas. The corpus callosum is exclusively present in placental mammals, while in acallosal mammals, most of the corpus callosum-related functions are carried out by the anterior commissure. The exact contribution of these two structures and of interhemispheric transfer in hearing in humans is still a matter of debate. In more recent years, human behavioural studies which employ psychoacoustic tasks designed to tap into interhemispheric transfer, combined with sophisticated neuroimaging paradigms, have helped to interpret information from animal experiments and post-mortem studies. This review will summarize and discuss the available information of the contributions of the human interhemispheric pathway in hearing in humans from behavioural, neuroimaging and histopathological studies in humans.

Original languageEnglish (US)
Pages (from-to)170-182
Number of pages13
JournalBrain Research Reviews
Volume56
Issue number1
DOIs
StatePublished - Nov 2007

Keywords

  • Anterior commissure
  • Auditory processing
  • Corpus callosum
  • Dichotic test
  • Interhemispheric transfer
  • Localization

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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