The Safety on the TCR Trigger

Michael S Kuhns, Mark M. Davis

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

Original languageEnglish (US)
Pages (from-to)594-596
Number of pages3
JournalCell
Volume135
Issue number4
DOIs
StatePublished - Nov 14 2008
Externally publishedYes

Fingerprint

T-Cell Antigen Receptor
Safety
Cell membranes
Tyrosine
Chemical activation
Cell Membrane

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

The Safety on the TCR Trigger. / Kuhns, Michael S; Davis, Mark M.

In: Cell, Vol. 135, No. 4, 14.11.2008, p. 594-596.

Research output: Contribution to journalArticle

Kuhns, Michael S ; Davis, Mark M. / The Safety on the TCR Trigger. In: Cell. 2008 ; Vol. 135, No. 4. pp. 594-596.
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