The Safety on the TCR Trigger

Michael S. Kuhns, Mark M. Davis

Research output: Contribution to journalShort survey

37 Scopus citations

Abstract

In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

Original languageEnglish (US)
Pages (from-to)594-596
Number of pages3
JournalCell
Volume135
Issue number4
DOIs
StatePublished - Nov 14 2008
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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