The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root

Laura Di Laurenzio, Joanna Wysocka-Diller, Jocelyn E. Malamy, Leonard Pysh, Yrjo Helariutta, Glenn Freshour, Michael G. Hahn, Kenneth A Feldmann, Philip N. Benfey

Research output: Contribution to journalArticle

689 Citations (Scopus)

Abstract

In the Arabidopsis root meristem, initial cells undergo asymmetric divisions to generate the cell lineages of the root. The scarecrow mutation results in roots that are missing one cell layer owing to the disruption of an asymmetric division that normally generates cortex and endodermis. Tissue- specific markers indicate that a heterogeneous cell type is formed in the mutant. The deduced amino acid sequence of SCARECROW (SCR) suggests that it is a member of a novel family of putative transcription factors. SCR is expressed in the cortex/endodermal initial cells and in the endodermal cell lineage. Tissue-specific expression is regulated at the transcriptional level. These results indicate a key role for SCR in regulating the radial organization of the root.

Original languageEnglish (US)
Pages (from-to)423-433
Number of pages11
JournalCell
Volume86
Issue number3
DOIs
StatePublished - Aug 9 1996

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Asymmetric Cell Division
Arabidopsis
Genes
Cells
Cell Lineage
Tissue
Transcription Factors
Meristem
Amino Acids
Amino Acid Sequence
Mutation

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Di Laurenzio, L., Wysocka-Diller, J., Malamy, J. E., Pysh, L., Helariutta, Y., Freshour, G., ... Benfey, P. N. (1996). The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. Cell, 86(3), 423-433. https://doi.org/10.1016/S0092-8674(00)80115-4

The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. / Di Laurenzio, Laura; Wysocka-Diller, Joanna; Malamy, Jocelyn E.; Pysh, Leonard; Helariutta, Yrjo; Freshour, Glenn; Hahn, Michael G.; Feldmann, Kenneth A; Benfey, Philip N.

In: Cell, Vol. 86, No. 3, 09.08.1996, p. 423-433.

Research output: Contribution to journalArticle

Di Laurenzio, L, Wysocka-Diller, J, Malamy, JE, Pysh, L, Helariutta, Y, Freshour, G, Hahn, MG, Feldmann, KA & Benfey, PN 1996, 'The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root', Cell, vol. 86, no. 3, pp. 423-433. https://doi.org/10.1016/S0092-8674(00)80115-4
Di Laurenzio, Laura ; Wysocka-Diller, Joanna ; Malamy, Jocelyn E. ; Pysh, Leonard ; Helariutta, Yrjo ; Freshour, Glenn ; Hahn, Michael G. ; Feldmann, Kenneth A ; Benfey, Philip N. / The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. In: Cell. 1996 ; Vol. 86, No. 3. pp. 423-433.
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