The tucson children's respiratory study: I. Design and implementation of a prospective study of acute and chronic respiratory illness in children

Lynn M. Taussig, Anne L Wright, Wayne J Morgan, H. Robert Harrison, C. George Ray

Research output: Contribution to journalArticle

153 Citations (Scopus)

Abstract

The Tucson Children's Respiratory Study, Tucson, Arizona, has been established as a long-term, longitudinal, prospective study of the risk factors for acute lower respiratory tract illnesses in early childhood and for chronic obstructive airways disease in later life. A total of 1,246 newborns were enrolled into the study between May 1980 and January 1984, representing 78% of eligible infants. Cord blood for immunologic studies, neonatal blood specimens for blood counts and differentials, and blood specimens at nine to 15 months of age for immunologic studies, blood counts, and differentials have been obtained on the majority of enrolled children. Pre-illness physiologic and more detailed immunologic studies have also been done on large subgroups of subjects. The majority of lower respiratory tract illnesses suffered by these children in the first three years of life have been assessed in detail for etiologic agents by means of culture and serologic techniques; 1,052 illnesses have been evaluated thus far. The type of illness and nature of etiologic agents are very similar to those reported in other epidemiologic studies. Thus, this group of enrolled infants and their family members constitute an appropriate population for the long-term study of risk factors for acute and chronic respiratory disorders.

Original languageEnglish (US)
Pages (from-to)1219-1231
Number of pages13
JournalAmerican Journal of Epidemiology
Volume129
Issue number6
StatePublished - Jun 1989

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Chronic Disease
Prospective Studies
Respiratory System
Culture Techniques
Fetal Blood
Chronic Obstructive Pulmonary Disease
Longitudinal Studies
Epidemiologic Studies
Newborn Infant
Population

Keywords

  • Epidemiologic methods
  • Longitudinal studies
  • Lung diseases
  • Obstructive
  • Prospective studies
  • Respiratory tract infections

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

Cite this

The tucson children's respiratory study : I. Design and implementation of a prospective study of acute and chronic respiratory illness in children. / Taussig, Lynn M.; Wright, Anne L; Morgan, Wayne J; Harrison, H. Robert; Ray, C. George.

In: American Journal of Epidemiology, Vol. 129, No. 6, 06.1989, p. 1219-1231.

Research output: Contribution to journalArticle

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