The ultrastructure of the thin limbs of Henle in kidneys of the desert heteromyid (Perognathus penicillatus)

Raymond B Nagle, E. M. Altschuler, D. C. Dobyan, S. Dong, R. E. Bulger

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The thin limbs of both long- and short-looped nephrons in Perognathus kidneys were studied with transmission and scanning electron microscopy. The superficial nephrons have a short thin limb located in the vascular bundles of the outer medulla and are characterized by a simple, low-lying epithelium (0.4 ± 0.1 μ thickness). In contrast, the first descending part of the thin limb of the majority of midcortical and juxtamedullary nephrons has a relatively thick epithelium (1.7 ± 0.6 μ in thickness) with marked lateral and basal interdigitation and a dense surface covering of microvilli. The remaining part of the long descending thin limb is relatively simple with a low-lying epithelium (0.6 ± 0.1 μ in thickness), decorated on its surface by sparse microplicae. The bend of the loop and the ascending limb are covered by a very simple low-lying epithelium (0.6 ± 0.2 μ in thickness) with relatively little surface modification. The extreme urine-concentrating ability of Perognathus does not appear to be due to the development of a unique thin loop epithelium but rather to the extensive length of the inner and outer medulla.

Original languageEnglish (US)
Pages (from-to)33-47
Number of pages15
JournalAmerican Journal of Anatomy
Volume161
Issue number1
DOIs
StatePublished - 1981

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Extremities
Epithelium
Nephrons
Kidney
Kidney Concentrating Ability
Scanning Transmission Electron Microscopy
Microvilli
Blood Vessels

ASJC Scopus subject areas

  • Anatomy

Cite this

The ultrastructure of the thin limbs of Henle in kidneys of the desert heteromyid (Perognathus penicillatus). / Nagle, Raymond B; Altschuler, E. M.; Dobyan, D. C.; Dong, S.; Bulger, R. E.

In: American Journal of Anatomy, Vol. 161, No. 1, 1981, p. 33-47.

Research output: Contribution to journalArticle

Nagle, Raymond B ; Altschuler, E. M. ; Dobyan, D. C. ; Dong, S. ; Bulger, R. E. / The ultrastructure of the thin limbs of Henle in kidneys of the desert heteromyid (Perognathus penicillatus). In: American Journal of Anatomy. 1981 ; Vol. 161, No. 1. pp. 33-47.
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