The use of two measures of health-related quality of life in HIV-infected individuals: A cross-sectional comparison

A. E. Copfer, Neil M. Ampel, T. E. Hughes, K. J. Gregor, C. L. Dols, S. J. Coons, K. Colgan, A. W. Wu

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Two measures of health-related quality of life in 65 HIV-infected individuals were compared in a cross-sectional design. The Quality of WeIl-Being Scale (QWB) results in a single score ranging from death to perfect hearth. The MOS-HIV Hearth Survey (MOS-HIV, 34 item version) gives scores in 11 dimensions. The QWB score distinguished subjects with AIDS from those who were asymptomatic (p = 0.027). For the seven multi-item scares of the MOS-HIV, Cronbach's alpha ranged from 0.85-0.95, indicating good internal consistency reliability. Clinical HIV-infection status was significantly associated with the dimensions of Overall Health (p = 0.002), Role Function (p = 0.022), Social Function (p = 0.037), Energy/Fatigue (p = 0.027) and Health Distress (p = 0.025). All eleven dimensions of the MOS-HIV were significantly correlated with the QWB score (Spearman's coefficient = 0.405-0.670; for all, p < 0.01) and the QWB score could be predicted from the MOS-HIV dimension scores using multiple regression. The QWB and the MOS-HIV may be useful in assessing health-related quality of life in patients infected with HIV.

Original languageEnglish (US)
Pages (from-to)281-286
Number of pages6
JournalQuality of Life Research
Volume5
Issue number2
DOIs
StatePublished - 1996

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Quality of Life
HIV
Health
HIV Infections
Fatigue
Acquired Immunodeficiency Syndrome

Keywords

  • Acquired immunodeficiency Syndrome
  • Health status
  • HIV-infection
  • Quality of life
  • Questionnaires

ASJC Scopus subject areas

  • Rehabilitation
  • Nursing(all)

Cite this

The use of two measures of health-related quality of life in HIV-infected individuals : A cross-sectional comparison. / Copfer, A. E.; Ampel, Neil M.; Hughes, T. E.; Gregor, K. J.; Dols, C. L.; Coons, S. J.; Colgan, K.; Wu, A. W.

In: Quality of Life Research, Vol. 5, No. 2, 1996, p. 281-286.

Research output: Contribution to journalArticle

Copfer, A. E. ; Ampel, Neil M. ; Hughes, T. E. ; Gregor, K. J. ; Dols, C. L. ; Coons, S. J. ; Colgan, K. ; Wu, A. W. / The use of two measures of health-related quality of life in HIV-infected individuals : A cross-sectional comparison. In: Quality of Life Research. 1996 ; Vol. 5, No. 2. pp. 281-286.
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