Therapeutic Strategies to Limit Lung Endothelial Cell Permeability

Rachel K. Wolfson, Gabriel Lang, Jeff Jacobson, Joe G.N. Garcia

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
Original languageEnglish (US)
Title of host publicationThe Pulmonary Endothelium
Subtitle of host publicationFunction in health and disease
PublisherJohn Wiley & Sons, Ltd
Pages337-354
Number of pages18
ISBN (Print)9780470723616
DOIs
StatePublished - Sep 11 2009
Externally publishedYes

Keywords

  • Acute (inflammatory) lung injury (ALI)
  • Intracellular signaling pathways and EC edemagenic agents
  • Methylnaltrexone (MNTX) - peripherally restricted mu opioid receptor (mOP-R) antagonist
  • Oxidized phospholipids
  • Receptor-mediated barrier protection - role of RAC GTPase
  • S1P
  • Simvastatin-mediated thrombin inhibition
  • Sphingolipid from sphingosine phosphorylation
  • Therapeutic strategies limiting lung endothelial cell permeability
  • Vascular endothelium - primary cellular target in physiologic derangement

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Wolfson, R. K., Lang, G., Jacobson, J., & Garcia, J. G. N. (2009). Therapeutic Strategies to Limit Lung Endothelial Cell Permeability. In The Pulmonary Endothelium: Function in health and disease (pp. 337-354). John Wiley & Sons, Ltd. https://doi.org/10.1002/9780470747490.ch21