Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity

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Abstract

The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.

Original languageEnglish (US)
Article numbere202010172
JournalJournal of Cell Biology
Volume219
Issue number12
DOIs
StatePublished - Dec 7 2020

ASJC Scopus subject areas

  • Cell Biology

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