Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: Initial results using highly accelerated parallel acquisition

Kambiz Nael, Michael Fenchel, Noriko Salamon, Gary R. Duckwiler, Gerhard Laub, J. Paul Finn, J. Pablo Villablanca

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

OBJECTIVE: The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS: Ten patients (4 male, 6 female; age, 38-76 years) with suspected cerebrovascular disease were prospectively studied on a 32-channel 3.0 T MR system. After a single intravenous contrast injection, high spatial resolution 3D CE-MR angiography of the entire supraaortic arteries was performed followed immediately by 3D cerebral CE-MR venography. By using a fast 3D gradient-recalled-echo sequence with elliptic centric k-space ordering and highly accelerated parallel acquisition (acceleration factor 3 and 2 in phase and slice encoding direction, respectively), 3D cerebral CE-MR venography was acquired with voxel dimensions of 0.7 × 0.7 × 0.8 mm in 24 seconds. Image evaluation was performed independently by 2 neuroradiologists for overall image quality, presence of noise, and artifacts. The image quality of 30 venous segments was evaluated in each subject using a 1 to 4 scoring scale. In 2 patients, catheter angiography was available for correlation. Statistical analysis of data was performed by using Wilcoxon rank sum test and kappa coefficient. RESULTS: All studies were determined to be of diagnostic image quality by both observers. The majority (90%) of cerebral venous segments were evaluated to be of diagnostic image quality (median, 3; range, 3-4) by both readers and with excellent interobserver agreement (κ = 0.86; 95% confidence interval, 0.79-0.93). One meningioma invading the superior sagittal sinus and one superior sagittal sinus fistula were detected subsequently confirmed by conventional angiography. CONCLUSION: High spatial resolution 3D cerebral CE-MR venography is feasible and promising. Using a 32-channel 3.0 T system combined with multichannel array coils effectively supports highly accelerated parallel imaging, enabling subsequent acquisition of both high spatial resolution CE-MR angiography and CE-MR venography after a single contrast injection without impairing the image quality. More extensive clinical studies are warranted to establish the range of applications and confirm the accuracy of this technique.

Original languageEnglish (US)
Pages (from-to)763-768
Number of pages6
JournalInvestigative Radiology
Volume41
Issue number10
DOIs
StatePublished - Oct 2006
Externally publishedYes

Fingerprint

Phlebography
Magnetic Resonance Spectroscopy
Superior Sagittal Sinus
Magnetic Resonance Angiography
Nonparametric Statistics
Angiography
Cerebrovascular Disorders
Statistical Data Interpretation
Meningioma
Intravenous Injections
Artifacts
Fistula
Noise
Catheters
Arteries
Confidence Intervals
Injections

Keywords

  • 3.0 Tesla
  • 3D cerebral venography
  • Contrast-enhanced MR venography
  • High magnetic field
  • Parallel acquisition techniques

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla : Initial results using highly accelerated parallel acquisition. / Nael, Kambiz; Fenchel, Michael; Salamon, Noriko; Duckwiler, Gary R.; Laub, Gerhard; Finn, J. Paul; Villablanca, J. Pablo.

In: Investigative Radiology, Vol. 41, No. 10, 10.2006, p. 763-768.

Research output: Contribution to journalArticle

Nael, Kambiz ; Fenchel, Michael ; Salamon, Noriko ; Duckwiler, Gary R. ; Laub, Gerhard ; Finn, J. Paul ; Villablanca, J. Pablo. / Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla : Initial results using highly accelerated parallel acquisition. In: Investigative Radiology. 2006 ; Vol. 41, No. 10. pp. 763-768.
@article{60a42692df6d4577942872074cd98812,
title = "Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: Initial results using highly accelerated parallel acquisition",
abstract = "OBJECTIVE: The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS: Ten patients (4 male, 6 female; age, 38-76 years) with suspected cerebrovascular disease were prospectively studied on a 32-channel 3.0 T MR system. After a single intravenous contrast injection, high spatial resolution 3D CE-MR angiography of the entire supraaortic arteries was performed followed immediately by 3D cerebral CE-MR venography. By using a fast 3D gradient-recalled-echo sequence with elliptic centric k-space ordering and highly accelerated parallel acquisition (acceleration factor 3 and 2 in phase and slice encoding direction, respectively), 3D cerebral CE-MR venography was acquired with voxel dimensions of 0.7 × 0.7 × 0.8 mm in 24 seconds. Image evaluation was performed independently by 2 neuroradiologists for overall image quality, presence of noise, and artifacts. The image quality of 30 venous segments was evaluated in each subject using a 1 to 4 scoring scale. In 2 patients, catheter angiography was available for correlation. Statistical analysis of data was performed by using Wilcoxon rank sum test and kappa coefficient. RESULTS: All studies were determined to be of diagnostic image quality by both observers. The majority (90{\%}) of cerebral venous segments were evaluated to be of diagnostic image quality (median, 3; range, 3-4) by both readers and with excellent interobserver agreement (κ = 0.86; 95{\%} confidence interval, 0.79-0.93). One meningioma invading the superior sagittal sinus and one superior sagittal sinus fistula were detected subsequently confirmed by conventional angiography. CONCLUSION: High spatial resolution 3D cerebral CE-MR venography is feasible and promising. Using a 32-channel 3.0 T system combined with multichannel array coils effectively supports highly accelerated parallel imaging, enabling subsequent acquisition of both high spatial resolution CE-MR angiography and CE-MR venography after a single contrast injection without impairing the image quality. More extensive clinical studies are warranted to establish the range of applications and confirm the accuracy of this technique.",
keywords = "3.0 Tesla, 3D cerebral venography, Contrast-enhanced MR venography, High magnetic field, Parallel acquisition techniques",
author = "Kambiz Nael and Michael Fenchel and Noriko Salamon and Duckwiler, {Gary R.} and Gerhard Laub and Finn, {J. Paul} and Villablanca, {J. Pablo}",
year = "2006",
month = "10",
doi = "10.1097/01.rli.0000236992.21065.04",
language = "English (US)",
volume = "41",
pages = "763--768",
journal = "Investigative Radiology",
issn = "0020-9996",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

TY - JOUR

T1 - Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla

T2 - Initial results using highly accelerated parallel acquisition

AU - Nael, Kambiz

AU - Fenchel, Michael

AU - Salamon, Noriko

AU - Duckwiler, Gary R.

AU - Laub, Gerhard

AU - Finn, J. Paul

AU - Villablanca, J. Pablo

PY - 2006/10

Y1 - 2006/10

N2 - OBJECTIVE: The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS: Ten patients (4 male, 6 female; age, 38-76 years) with suspected cerebrovascular disease were prospectively studied on a 32-channel 3.0 T MR system. After a single intravenous contrast injection, high spatial resolution 3D CE-MR angiography of the entire supraaortic arteries was performed followed immediately by 3D cerebral CE-MR venography. By using a fast 3D gradient-recalled-echo sequence with elliptic centric k-space ordering and highly accelerated parallel acquisition (acceleration factor 3 and 2 in phase and slice encoding direction, respectively), 3D cerebral CE-MR venography was acquired with voxel dimensions of 0.7 × 0.7 × 0.8 mm in 24 seconds. Image evaluation was performed independently by 2 neuroradiologists for overall image quality, presence of noise, and artifacts. The image quality of 30 venous segments was evaluated in each subject using a 1 to 4 scoring scale. In 2 patients, catheter angiography was available for correlation. Statistical analysis of data was performed by using Wilcoxon rank sum test and kappa coefficient. RESULTS: All studies were determined to be of diagnostic image quality by both observers. The majority (90%) of cerebral venous segments were evaluated to be of diagnostic image quality (median, 3; range, 3-4) by both readers and with excellent interobserver agreement (κ = 0.86; 95% confidence interval, 0.79-0.93). One meningioma invading the superior sagittal sinus and one superior sagittal sinus fistula were detected subsequently confirmed by conventional angiography. CONCLUSION: High spatial resolution 3D cerebral CE-MR venography is feasible and promising. Using a 32-channel 3.0 T system combined with multichannel array coils effectively supports highly accelerated parallel imaging, enabling subsequent acquisition of both high spatial resolution CE-MR angiography and CE-MR venography after a single contrast injection without impairing the image quality. More extensive clinical studies are warranted to establish the range of applications and confirm the accuracy of this technique.

AB - OBJECTIVE: The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS: Ten patients (4 male, 6 female; age, 38-76 years) with suspected cerebrovascular disease were prospectively studied on a 32-channel 3.0 T MR system. After a single intravenous contrast injection, high spatial resolution 3D CE-MR angiography of the entire supraaortic arteries was performed followed immediately by 3D cerebral CE-MR venography. By using a fast 3D gradient-recalled-echo sequence with elliptic centric k-space ordering and highly accelerated parallel acquisition (acceleration factor 3 and 2 in phase and slice encoding direction, respectively), 3D cerebral CE-MR venography was acquired with voxel dimensions of 0.7 × 0.7 × 0.8 mm in 24 seconds. Image evaluation was performed independently by 2 neuroradiologists for overall image quality, presence of noise, and artifacts. The image quality of 30 venous segments was evaluated in each subject using a 1 to 4 scoring scale. In 2 patients, catheter angiography was available for correlation. Statistical analysis of data was performed by using Wilcoxon rank sum test and kappa coefficient. RESULTS: All studies were determined to be of diagnostic image quality by both observers. The majority (90%) of cerebral venous segments were evaluated to be of diagnostic image quality (median, 3; range, 3-4) by both readers and with excellent interobserver agreement (κ = 0.86; 95% confidence interval, 0.79-0.93). One meningioma invading the superior sagittal sinus and one superior sagittal sinus fistula were detected subsequently confirmed by conventional angiography. CONCLUSION: High spatial resolution 3D cerebral CE-MR venography is feasible and promising. Using a 32-channel 3.0 T system combined with multichannel array coils effectively supports highly accelerated parallel imaging, enabling subsequent acquisition of both high spatial resolution CE-MR angiography and CE-MR venography after a single contrast injection without impairing the image quality. More extensive clinical studies are warranted to establish the range of applications and confirm the accuracy of this technique.

KW - 3.0 Tesla

KW - 3D cerebral venography

KW - Contrast-enhanced MR venography

KW - High magnetic field

KW - Parallel acquisition techniques

UR - http://www.scopus.com/inward/record.url?scp=33748753407&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748753407&partnerID=8YFLogxK

U2 - 10.1097/01.rli.0000236992.21065.04

DO - 10.1097/01.rli.0000236992.21065.04

M3 - Article

C2 - 16971800

AN - SCOPUS:33748753407

VL - 41

SP - 763

EP - 768

JO - Investigative Radiology

JF - Investigative Radiology

SN - 0020-9996

IS - 10

ER -