Thrombosis

D. Nguyen, Bruce M Coull

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Thrombosis resulting from various pathologies is the underlying cause of the majority of ischemic strokes. Hemostasis is the complex and highly regulated system that helps to maintain the integrity of blood and the vasculature. Maintenance of blood flow depends upon an intact and fully functional vascular endothelium. Thrombosis is one of the pathological consequences when the hemostatic system is activated within the circulation itself often as a result of disruption or derangements in the vascular endothelium. Although the concept dates back at least 250. years to the time of the Scottish surgeon John Hunter, the current understanding of how thrombotic events happen increasingly links inflammatory mechanisms with thrombosis.

Original languageEnglish (US)
Title of host publicationPrimer on Cerebrovascular Diseases
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages108-113
Number of pages6
ISBN (Print)9780128030585
DOIs
StatePublished - Mar 7 2017

Fingerprint

Thrombosis
Vascular Endothelium
Hemostatics
Hemostasis
Stroke
Maintenance
Pathology
Surgeons

Keywords

  • Direct oral anticoagulants
  • Endothelium
  • Fibrinolysis
  • Hemostasis
  • Ischemic stroke
  • Thrombophilia
  • Thrombosis

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Nguyen, D., & Coull, B. M. (2017). Thrombosis. In Primer on Cerebrovascular Diseases: Second Edition (pp. 108-113). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-803058-5.00021-7

Thrombosis. / Nguyen, D.; Coull, Bruce M.

Primer on Cerebrovascular Diseases: Second Edition. Elsevier Inc., 2017. p. 108-113.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nguyen, D & Coull, BM 2017, Thrombosis. in Primer on Cerebrovascular Diseases: Second Edition. Elsevier Inc., pp. 108-113. https://doi.org/10.1016/B978-0-12-803058-5.00021-7
Nguyen D, Coull BM. Thrombosis. In Primer on Cerebrovascular Diseases: Second Edition. Elsevier Inc. 2017. p. 108-113 https://doi.org/10.1016/B978-0-12-803058-5.00021-7
Nguyen, D. ; Coull, Bruce M. / Thrombosis. Primer on Cerebrovascular Diseases: Second Edition. Elsevier Inc., 2017. pp. 108-113
@inbook{cbd11a692de848d79186e64b76147f02,
title = "Thrombosis",
abstract = "Thrombosis resulting from various pathologies is the underlying cause of the majority of ischemic strokes. Hemostasis is the complex and highly regulated system that helps to maintain the integrity of blood and the vasculature. Maintenance of blood flow depends upon an intact and fully functional vascular endothelium. Thrombosis is one of the pathological consequences when the hemostatic system is activated within the circulation itself often as a result of disruption or derangements in the vascular endothelium. Although the concept dates back at least 250. years to the time of the Scottish surgeon John Hunter, the current understanding of how thrombotic events happen increasingly links inflammatory mechanisms with thrombosis.",
keywords = "Direct oral anticoagulants, Endothelium, Fibrinolysis, Hemostasis, Ischemic stroke, Thrombophilia, Thrombosis",
author = "D. Nguyen and Coull, {Bruce M}",
year = "2017",
month = "3",
day = "7",
doi = "10.1016/B978-0-12-803058-5.00021-7",
language = "English (US)",
isbn = "9780128030585",
pages = "108--113",
booktitle = "Primer on Cerebrovascular Diseases",
publisher = "Elsevier Inc.",
address = "United States",

}

TY - CHAP

T1 - Thrombosis

AU - Nguyen, D.

AU - Coull, Bruce M

PY - 2017/3/7

Y1 - 2017/3/7

N2 - Thrombosis resulting from various pathologies is the underlying cause of the majority of ischemic strokes. Hemostasis is the complex and highly regulated system that helps to maintain the integrity of blood and the vasculature. Maintenance of blood flow depends upon an intact and fully functional vascular endothelium. Thrombosis is one of the pathological consequences when the hemostatic system is activated within the circulation itself often as a result of disruption or derangements in the vascular endothelium. Although the concept dates back at least 250. years to the time of the Scottish surgeon John Hunter, the current understanding of how thrombotic events happen increasingly links inflammatory mechanisms with thrombosis.

AB - Thrombosis resulting from various pathologies is the underlying cause of the majority of ischemic strokes. Hemostasis is the complex and highly regulated system that helps to maintain the integrity of blood and the vasculature. Maintenance of blood flow depends upon an intact and fully functional vascular endothelium. Thrombosis is one of the pathological consequences when the hemostatic system is activated within the circulation itself often as a result of disruption or derangements in the vascular endothelium. Although the concept dates back at least 250. years to the time of the Scottish surgeon John Hunter, the current understanding of how thrombotic events happen increasingly links inflammatory mechanisms with thrombosis.

KW - Direct oral anticoagulants

KW - Endothelium

KW - Fibrinolysis

KW - Hemostasis

KW - Ischemic stroke

KW - Thrombophilia

KW - Thrombosis

UR - http://www.scopus.com/inward/record.url?scp=85028293882&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85028293882&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-803058-5.00021-7

DO - 10.1016/B978-0-12-803058-5.00021-7

M3 - Chapter

AN - SCOPUS:85028293882

SN - 9780128030585

SP - 108

EP - 113

BT - Primer on Cerebrovascular Diseases

PB - Elsevier Inc.

ER -