Tomographic small-animal imaging using a high-resolution semiconductor camera

G. A. Kastis, M. C. Wu, S. J. Balzer, D. W. Wilson, Lars R Furenlid, G. Stevenson, H. B. Barber, Harrison H Barrett, J. M. Woolfenden, P. Kelly, M. Appleby

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

We have developed a high-resolution, compact semiconductor camera for nuclear medicine applications. The modular unit has been used to obtain tomographic images of phantoms and mice. The system consists of a 64 × 64 CdZnTe detector array and a parallel-hole tungsten collimator mounted inside a 17 cm × 5.3 cm × 3.7 cm tungsten-aluminum housing. The detector is a 2.5 cm × 2.5 cm × 0.15 cm slab of CdZnTe connected to a 64 × 64 multiplexer readout via indium-bump bonding. The collimator is 7mm thick, with a 0.38 mm pitch that matches the detector pixel pitch. We obtained a series of projections by rotating the object in front of the camera. The axis of rotation was vertical and about 1.5 cm away from the collimator face. Mouse holders were made out of acrylic plastic tubing to facilitate rotation and the administration of gas anesthetic. Acquisition times were varied from 60 sec to 90 sec per image for a total of 60 projections at an equal spacing of 6 degrees between projections. We present tomographic images of a line phantom and mouse bone scan and assess the properties of the system. The reconstructed images demonstrate spatial resolution on the order of 1-21 mm.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
EditorsD. Merelli, J. Surget, M. Ulma
Volume3
StatePublished - 2000
Event2000 IEEE Nuclear Science Symposium Conference Record - Lyon, France
Duration: Oct 15 2000Oct 20 2000

Other

Other2000 IEEE Nuclear Science Symposium Conference Record
CountryFrance
CityLyon
Period10/15/0010/20/00

Fingerprint

Animals
Cameras
Semiconductor materials
Detectors
Imaging techniques
Tungsten
Nuclear medicine
Anesthetics
Tubing
Indium
Acrylics
Bone
Pixels
Plastics
Aluminum
Gases

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Kastis, G. A., Wu, M. C., Balzer, S. J., Wilson, D. W., Furenlid, L. R., Stevenson, G., ... Appleby, M. (2000). Tomographic small-animal imaging using a high-resolution semiconductor camera. In D. Merelli, J. Surget, & M. Ulma (Eds.), IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 3)

Tomographic small-animal imaging using a high-resolution semiconductor camera. / Kastis, G. A.; Wu, M. C.; Balzer, S. J.; Wilson, D. W.; Furenlid, Lars R; Stevenson, G.; Barber, H. B.; Barrett, Harrison H; Woolfenden, J. M.; Kelly, P.; Appleby, M.

IEEE Nuclear Science Symposium and Medical Imaging Conference. ed. / D. Merelli; J. Surget; M. Ulma. Vol. 3 2000.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kastis, GA, Wu, MC, Balzer, SJ, Wilson, DW, Furenlid, LR, Stevenson, G, Barber, HB, Barrett, HH, Woolfenden, JM, Kelly, P & Appleby, M 2000, Tomographic small-animal imaging using a high-resolution semiconductor camera. in D Merelli, J Surget & M Ulma (eds), IEEE Nuclear Science Symposium and Medical Imaging Conference. vol. 3, 2000 IEEE Nuclear Science Symposium Conference Record, Lyon, France, 10/15/00.
Kastis GA, Wu MC, Balzer SJ, Wilson DW, Furenlid LR, Stevenson G et al. Tomographic small-animal imaging using a high-resolution semiconductor camera. In Merelli D, Surget J, Ulma M, editors, IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 3. 2000
Kastis, G. A. ; Wu, M. C. ; Balzer, S. J. ; Wilson, D. W. ; Furenlid, Lars R ; Stevenson, G. ; Barber, H. B. ; Barrett, Harrison H ; Woolfenden, J. M. ; Kelly, P. ; Appleby, M. / Tomographic small-animal imaging using a high-resolution semiconductor camera. IEEE Nuclear Science Symposium and Medical Imaging Conference. editor / D. Merelli ; J. Surget ; M. Ulma. Vol. 3 2000.
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