TORCing Neutrophil Chemotaxis

Pascale G. Charest, Richard A. Firtel

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

During cell migration, chemoattractant-induced signaling pathways determine the direction of movement by controlling the spatiotemporal dynamics of cytoskeletal components. In this issue of Developmental Cell, Liu et al. report that the target of rapamycin complex 2 (TORC2) controls cell polarity and chemotaxis through regulation of both F-actin and myosin II in migrating neutrophils.

Original languageEnglish (US)
Pages (from-to)795-796
Number of pages2
JournalDevelopmental Cell
Volume19
Issue number6
DOIs
StatePublished - Dec 14 2010
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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