Toxicity of a phthalate ester in the diet of a penaied shrimp

James F. Hobson, Dean E. Carter, Donald V. Lightner

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The toxicity of di-2-ethylhexylphthalate (DEHP), a ubiquitous environmental pollutant, was measured experimentally as a contaminant in shrimp aquaculture feeds. Diets containing 40 to 50, 000 ppm DEHP were fed to Penaeus vannamei for 14 d at 4% body weight/d. DEHP concentrations in shrimp, diet, and water were measured by electron- capture gas chromatography. Who!e-body residues in shrimp were 18 ppm at the highest dose, and bioconcentration factors were inversely proportional to dose. DEHP in water was <1.7 ppb for all dose levels. No increased mortality or histopathological alterations were observed at any dose. Absorption of DEHP by P. vannamei was measured in static 24- and 96-h bioassays. Diets enriched with [l4C]DEHP to levels of 60, 600, and 6000 ppm were fed at 2% body weightjd. At all dose levels, 3.7% of total radioactivity was measured os body burden in shrimp and 40% as polar species in test water after 96 h. DEHP by oral administration was absorbed, metabolized, and excreted, and this process was linear with dose for the dose range studied.

Original languageEnglish (US)
Pages (from-to)959-968
Number of pages10
JournalJournal of Toxicology and Environmental Health
Volume13
Issue number4-6
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Toxicology
  • Pollution

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