Toxicity of a phthalate ester in the diet of a penaied shrimp

J. F. Hobson, D. E. Carter, Donald V Lightner

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The toxicity of di-2-ethylhexyl phthalate (DEHP), a ubiquitous environmental pollutant, was measured experimentally as a contaminant in shrimp aquaculture feeds. Diets containing 40 to 50,000 ppm DEHP were fed to Penaeus vannamei for 14 d at 4% body weight/d. DEHP concentrations in shrimp, diet, and water were measured by electron-capture gas chromatography. Whole-body residues in shrimp were 18 ppm at the highest dose, and bioconcentration factors were inversely proportional to dose. DEHP in water was ≤ 1.7 ppb for all dose levels. No increased mortality or histopathological alterations were observed at any dose. Absorption of DEHP by P. vannamei was measured in static 24- and 96-h bioassays. Diets enriched with [14C] DEHP to levels of 60, 600, and 6000 ppm were fed at 2% body weight/d. At all dose levels, 3.7% of total radioactivity was measured as body burden in shrimp and 40% as polar aspects in test water after 96 h. DEHP by oral administration was absorbed, metabolized, and excreted, and this process was linear with dose for the dose range studied.

Original languageEnglish (US)
Pages (from-to)959-968
Number of pages10
JournalJournal of Toxicology and Environmental Health
Volume13
Issue number4-6
StatePublished - 1984

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Nutrition
Toxicity
Esters
Diet
Water
Aquaculture
Bioassay
Radioactivity
Gas chromatography
Dosimetry
Impurities
Body Weight
Penaeidae
Electrons
Body Burden
Environmental Pollutants
phthalic acid
Biological Assay
Gas Chromatography
Oral Administration

ASJC Scopus subject areas

  • Pollution
  • Toxicology

Cite this

Toxicity of a phthalate ester in the diet of a penaied shrimp. / Hobson, J. F.; Carter, D. E.; Lightner, Donald V.

In: Journal of Toxicology and Environmental Health, Vol. 13, No. 4-6, 1984, p. 959-968.

Research output: Contribution to journalArticle

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