Trans-esophageal endoscopic ultrasound guided fine needle aspiration: A minimally invasive method for tissue sampling of mediastinal lymph nodes in thoracic malignancies

Manoop S. Bhutani, S. Suryaprasad, J. Moezzi, Y. Park, John T Cunningham, C. Payne

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: To report the utility and safety of trans-esophageal endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) for tissue diagnosis of mediastinal lymph nodes. Methods: Five patients (1=non small cell lung Ca, 1=breast Ca, 1=prostate Ca, 1=mediastinal adenopathy of ? origin, 1=squamous cell esophageal Ca) underwent EUS evaluation with radial and linear scanning echoendoscope at 7.5 MegaHertz after conscious sedation with intravenous diazepam and meperidine. Four of 5 patients had lymph nodes (LNs) in the subcarina or A-P window by CT Scan. Trans-esophageal fine needle aspiration of LNs in the subcarina or the A-P window was performed under real time ultrasound guidance. Two to 6 passes were made. There were no complications. Results: EUS guided lymph node FNA revealed metastatic squamous cell esophageal Ca in 1 patient and metastatic prostatic adenoca in another. The other 3 patients had a benign LN aspirate. Conclusion: EUS guided transesophageal FNA is a safe, minimally invasive technique to sample mediastinal LNs. Clinical Implications: EUS guided FNA of mediastinal LNs can play a significant role in staging thoracic malignancies e.g. lung Ca, esophageal Ca. A positive FNA for malignancy can avert more invasive procedures such as mediastinoscopy or surgery. We continue to perform this technique and study its clinical utility.

Original languageEnglish (US)
JournalChest
Volume110
Issue number4 SUPPL.
StatePublished - Oct 1996
Externally publishedYes

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Endoscopic Ultrasound-Guided Fine Needle Aspiration
Thorax
Lymph Nodes
Fine Needle Biopsy
Neoplasms
Epithelial Cells
Mediastinoscopy
Conscious Sedation
Lung
Meperidine
Diazepam
Prostate
Breast
Safety

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Trans-esophageal endoscopic ultrasound guided fine needle aspiration : A minimally invasive method for tissue sampling of mediastinal lymph nodes in thoracic malignancies. / Bhutani, Manoop S.; Suryaprasad, S.; Moezzi, J.; Park, Y.; Cunningham, John T; Payne, C.

In: Chest, Vol. 110, No. 4 SUPPL., 10.1996.

Research output: Contribution to journalArticle

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