Trauma as an etiologic and aggravating factor in multiple sclerosis

Colin R. Bamford; William A. Sibley; Cole Thies; Jose F. Laguna; Michael S. Smith; Katherine Clark

doi:10.1212/wnl.31.10.1229

Trauma as an etiologic and aggravating factor in multiple sclerosis

Colin R. Bamford, William A. Sibley, Cole Thies, Jose F. Laguna, Michael S. Smith, Katherine Clark

Neurology

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34 Scopus citations

Abstract

We carried out a retrospective and prospective epidemiologic study designed to detect an association between trauma and multiple sclerosis in 130 patients and 82 age- and sex-matched controls. Electrical injury was followed by an increased frequency of exacerbation, which did not achieve statistical significance. There was no statistically significant association between other types of trauma and onset or deterioration of the disease. These findings do not prove that such an association cannot exist for any one individual patient; however, they do not provide evidence to support this idea.

Original language	English (US)
Pages (from-to)	1229-1234
Number of pages	6
Journal	Neurology
Volume	31
Issue number	10
DOIs	https://doi.org/10.1212/wnl.31.10.1229
State	Published - Oct 1981

ASJC Scopus subject areas

Clinical Neurology

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AU - Clark, Katherine

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AB - We carried out a retrospective and prospective epidemiologic study designed to detect an association between trauma and multiple sclerosis in 130 patients and 82 age- and sex-matched controls. Electrical injury was followed by an increased frequency of exacerbation, which did not achieve statistical significance. There was no statistically significant association between other types of trauma and onset or deterioration of the disease. These findings do not prove that such an association cannot exist for any one individual patient; however, they do not provide evidence to support this idea.

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Trauma as an etiologic and aggravating factor in multiple sclerosis

Abstract

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