Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate

J. F. Barter, S. J. Soong, Kenneth D Hatch, J. W. Orr, E. C. Partridge, J. M. Austin, H. M. Shingleton

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Fifteen patients with nonmetastatic gestational trophoblastic disease were treated solely with methotrexate given orally rather than intramuscularly. Remission, defined as a β-human chorionic gonadotropin titer of <5 mIU/ml for 3 consecutive weeks, was attained in 13 (87%) of the 15 patients. Level of toxicity was acceptable. Patient comfort, convenience, and less time off work and in the physician's office are significant advantages to this efficacious, well-tolerated method of therapy.

Original languageEnglish (US)
Pages (from-to)1166-1168
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume157
Issue number5
StatePublished - 1987
Externally publishedYes

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Gestational Trophoblastic Disease
Methotrexate
Physicians' Offices
Chorionic Gonadotropin
Therapeutics
Patient Comfort

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Barter, J. F., Soong, S. J., Hatch, K. D., Orr, J. W., Partridge, E. C., Austin, J. M., & Shingleton, H. M. (1987). Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate. American Journal of Obstetrics and Gynecology, 157(5), 1166-1168.

Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate. / Barter, J. F.; Soong, S. J.; Hatch, Kenneth D; Orr, J. W.; Partridge, E. C.; Austin, J. M.; Shingleton, H. M.

In: American Journal of Obstetrics and Gynecology, Vol. 157, No. 5, 1987, p. 1166-1168.

Research output: Contribution to journalArticle

Barter, JF, Soong, SJ, Hatch, KD, Orr, JW, Partridge, EC, Austin, JM & Shingleton, HM 1987, 'Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate', American Journal of Obstetrics and Gynecology, vol. 157, no. 5, pp. 1166-1168.
Barter, J. F. ; Soong, S. J. ; Hatch, Kenneth D ; Orr, J. W. ; Partridge, E. C. ; Austin, J. M. ; Shingleton, H. M. / Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate. In: American Journal of Obstetrics and Gynecology. 1987 ; Vol. 157, No. 5. pp. 1166-1168.
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