Treatment planning of template-guided stereotaxic brain implants

Bruce A. Lulu, Wendell Lut, Baldassarre Stea, Thomas C. Cetas

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We have initiated a Phase I clinical trial of interstitial hyperthermia induced with inductively heated ferromagnetic implants in combination with Ir-192 implants for glioblastomas and anaplastic astrocytomas of the brain. For speed and accuracy of the implant procedure, and to control the radiation and thermal dose, a stereotaxic frame is used to position a template. We have modified the Brown-Roberts-Wells frame to be used with a variety of templates which we designed. On the morning of the implant procedure, a CT scan is done, and a CT-based treatment plan is then completed before the patient goes to the operating room. We also describe the CT-based treatment planning system developed to accommodate the template-guided implant and illustrate its clinical use.

Original languageEnglish (US)
Pages (from-to)951-955
Number of pages5
JournalInternational Journal of Radiation Oncology Biology Physics
Volume18
Issue number4
DOIs
StatePublished - 1990

Fingerprint

brain
planning
templates
Clinical Trials, Phase I
Induced Hyperthermia
Astrocytoma
Brain
Operating Rooms
Glioblastoma
morning
Hot Temperature
hyperthermia
Radiation
rooms
interstitials
Therapeutics
dosage
radiation

Keywords

  • CT-guided implants
  • Hyperthermia
  • Stereotaxic implants
  • Treatment planning

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation

Cite this

Treatment planning of template-guided stereotaxic brain implants. / Lulu, Bruce A.; Lut, Wendell; Stea, Baldassarre; Cetas, Thomas C.

In: International Journal of Radiation Oncology Biology Physics, Vol. 18, No. 4, 1990, p. 951-955.

Research output: Contribution to journalArticle

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