tsRNAs: The Swiss Army Knife for Translational Regulation

Junchao Shi, Yunfang Zhang, Tong Zhou, Qi Chen

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

tRNA-derived small RNAs (tsRNAs, or tRFs) are a new category of regulatory noncoding RNAs with versatile functions. Recent emerging studies have begun to unveil distinct features of tsRNAs based on their sequence, RNA modifications, and structures that differentially impact their functions towards regulating multiple aspects of translational control and ribosome biogenesis.

Original languageEnglish (US)
JournalTrends in Biochemical Sciences
DOIs
StateAccepted/In press - Jan 1 2018
Externally publishedYes

Keywords

  • ribosome
  • RNA modification
  • RNA structure
  • translational regulation
  • tRNA-derived small RNA

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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