Tumor inhibitory agents from Vauquelinia corymbosa (rosaceae)

E. R. Trumbull, E. Bianchi, D. J. Eckert, R. M. Wiedhopf, J. R. Cole

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

The chloroform extract of Vauquelinia corymbosa Correa has shown activity against the P‐388 lymphocytic leukemia test system. The constituents responsible for this activity were identified as uvaol, ursolic acid, and betulinic acid. Their identity was proven by melting point; mixed melting point; elemental analysis; IR, PMR, and mass spectra; and preparation of derivatives.

Original languageEnglish (US)
Pages (from-to)1407-1408
Number of pages2
JournalJournal of pharmaceutical sciences
Volume65
Issue number9
DOIs
StatePublished - Sep 1976

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Keywords

  • Antitumor agents, potential—uvaol, ursolic acid, and betulinic acid isolated from leaves and stems of Vauquelinia corymbosa, screened
  • Vauquelinia corymbosa—chloroform extract of leaves and stems, uvaol, ursolic acid, and betulinic acid isolated, screened for antitumor activity

ASJC Scopus subject areas

  • Pharmaceutical Science

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