Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae)

E. R. Trumbull, E. Bianchi, D. J. Eckert, R. M. Wiedhopf, Jack R Cole

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The chloroform extract of Vauquelinia corymbosa Correa has shown activity against the P 388 lymphocytic leukemia test system. The constituents responsible for this activity were identified as uvaol, ursolic acid, and betulinic acid. Their identity was proven by melting point; mixed melting point; elemental analysis; IR, PMR, and mass spectra; and preparation of derivatives.

Original languageEnglish (US)
Pages (from-to)1407-1408
Number of pages2
JournalJournal of Pharmaceutical Sciences
Volume65
Issue number9
StatePublished - 1976

Fingerprint

Rosaceae
Freezing
Melting point
Tumors
Lymphoid Leukemia
Chloroform
Neoplasms
Derivatives
Chemical analysis
uvaol
betulinic acid
ursolic acid

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Chemistry(all)
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science

Cite this

Trumbull, E. R., Bianchi, E., Eckert, D. J., Wiedhopf, R. M., & Cole, J. R. (1976). Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae). Journal of Pharmaceutical Sciences, 65(9), 1407-1408.

Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae). / Trumbull, E. R.; Bianchi, E.; Eckert, D. J.; Wiedhopf, R. M.; Cole, Jack R.

In: Journal of Pharmaceutical Sciences, Vol. 65, No. 9, 1976, p. 1407-1408.

Research output: Contribution to journalArticle

Trumbull, ER, Bianchi, E, Eckert, DJ, Wiedhopf, RM & Cole, JR 1976, 'Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae)', Journal of Pharmaceutical Sciences, vol. 65, no. 9, pp. 1407-1408.
Trumbull ER, Bianchi E, Eckert DJ, Wiedhopf RM, Cole JR. Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae). Journal of Pharmaceutical Sciences. 1976;65(9):1407-1408.
Trumbull, E. R. ; Bianchi, E. ; Eckert, D. J. ; Wiedhopf, R. M. ; Cole, Jack R. / Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae). In: Journal of Pharmaceutical Sciences. 1976 ; Vol. 65, No. 9. pp. 1407-1408.
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