Tumor‐inhibitory agent from Montezuma speciosissima (malvaceae)

S. D. Jolad, R. M. Wiedhopf, J. R. Cole

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The petroleum ether extract of Montezuma speciosissima Sesse and Moc. demonstrated tumor‐inhibiting properties in the P‐388 lymphocytic leukemia test system (3PS). The constituent responsible for this activity was shown to be a symmetrically substituted 2, 2′‐dinaphthol, identified as gossypol (C30H30O8).

Original languageEnglish (US)
Pages (from-to)1889-1890
Number of pages2
JournalJournal of pharmaceutical sciences
Volume64
Issue number11
DOIs
StatePublished - Nov 1975

Keywords

  • Gossypol—isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra, tumor inhibitory activity
  • Montezuma speciosissima—extract, PMR, UV, IR, and mass spectra, gossypol isolated
  • Tumor inhibition—gossypol, isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra

ASJC Scopus subject areas

  • Pharmaceutical Science

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