Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)

S. D. Jolad, R. M. Wiedhopf, J. R. Cole

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

The chloroform extract of Zaluzania robinsonii Sharp has shown activity against the P‐388 lymphocytic leukemia test system. The constituent responsible for this activity was a guaianolide, identified as zaluzanin C (15H18O3). The identity was proven by melting point, mixed melting point, elemental analysis, IR, PMR, mass spectroscopy, and preparation of derivatives.

Original languageEnglish (US)
Pages (from-to)1321-1322
Number of pages2
JournalJournal of pharmaceutical sciences
Volume63
Issue number8
DOIs
StatePublished - Aug 1974

Keywords

  • Antitumor agents, potential—isolation, identification, and screening of zaluzanin C from Z. robinsonii
  • Zaluzania robinsonii (Compositae)—isolation and identification of zaluzanin C as tumor‐inhibiting agent
  • Zaluzanin C‐isolation and identification from Z. robinsonii, tested for tumor‐inhibitory activity

ASJC Scopus subject areas

  • Pharmaceutical Science

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