Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)

S. D. Jolad, R. M. Wiedhopf, J. R. Cole

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The chloroform extract of Zaluzania robinsonii Sharp has shown activity against the P‐388 lymphocytic leukemia test system. The constituent responsible for this activity was a guaianolide, identified as zaluzanin C (15H18O3). The identity was proven by melting point, mixed melting point, elemental analysis, IR, PMR, mass spectroscopy, and preparation of derivatives.

Original languageEnglish (US)
Pages (from-to)1321-1322
Number of pages2
JournalJournal of pharmaceutical sciences
Volume63
Issue number8
DOIs
StatePublished - Aug 1974

Keywords

  • Antitumor agents, potential—isolation, identification, and screening of zaluzanin C from Z. robinsonii
  • Zaluzania robinsonii (Compositae)—isolation and identification of zaluzanin C as tumor‐inhibiting agent
  • Zaluzanin C‐isolation and identification from Z. robinsonii, tested for tumor‐inhibitory activity

ASJC Scopus subject areas

  • Pharmaceutical Science

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