Ultrasound current source density imaging using a clinical intracardiac catheter

Qian Li, Yexian Qin, Pier Ingram, Russell S Witte, Zhaohui Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Radiofrequency catheter ablation for treatment of cardiac arrhythmia requires pre-surgical mapping of the heart's activation wave. However, modern cardiac mapping systems continue to suffer from significant limitations. We have proposed Ultrasound Current Source Density Imaging (UCSDI) as a new modality to map reentry currents in the heart. In this study, we focus on interfacing UCSDI with a clinical intra-cardiac catheter - a key step towards translating UCSDI to the clinic for guiding cardiac ablation therapy. Sensitivity of UCSDI combined with the catheter was tested in a tissue mimicking phantom and fresh excised porcine hear tissue. Effect of the recoding distance on the detection of UCSDI was also investigated. Sensitivity of UCSDI with catheter was 4.7 μV/mA (R 2 = 0.999) in cylindrical gel (0.9% NaCl), and 3.2 μV/mA (R 2 = 0.92) in porcine heart tissue. The AE signal was detectable more than 25 mm away from the source in cylindrical gel (0.9% NaCl).

Original languageEnglish (US)
Title of host publicationIEEE International Ultrasonics Symposium, IUS
Pages704-707
Number of pages4
DOIs
StatePublished - 2011
Event2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States
Duration: Oct 18 2011Oct 21 2011

Other

Other2011 IEEE International Ultrasonics Symposium, IUS 2011
CountryUnited States
CityOrlando, FL
Period10/18/1110/21/11

Fingerprint

ablation
gels
arrhythmia
reentry
translating
sensitivity
therapy
activation

Keywords

  • acoustoelectric effect
  • cardiac arrhythmia
  • catheter ablation
  • ECG, EKG, multi-electrode recording

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Li, Q., Qin, Y., Ingram, P., Witte, R. S., & Wang, Z. (2011). Ultrasound current source density imaging using a clinical intracardiac catheter. In IEEE International Ultrasonics Symposium, IUS (pp. 704-707). [6293729] https://doi.org/10.1109/ULTSYM.2011.0171

Ultrasound current source density imaging using a clinical intracardiac catheter. / Li, Qian; Qin, Yexian; Ingram, Pier; Witte, Russell S; Wang, Zhaohui.

IEEE International Ultrasonics Symposium, IUS. 2011. p. 704-707 6293729.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Li, Q, Qin, Y, Ingram, P, Witte, RS & Wang, Z 2011, Ultrasound current source density imaging using a clinical intracardiac catheter. in IEEE International Ultrasonics Symposium, IUS., 6293729, pp. 704-707, 2011 IEEE International Ultrasonics Symposium, IUS 2011, Orlando, FL, United States, 10/18/11. https://doi.org/10.1109/ULTSYM.2011.0171
Li Q, Qin Y, Ingram P, Witte RS, Wang Z. Ultrasound current source density imaging using a clinical intracardiac catheter. In IEEE International Ultrasonics Symposium, IUS. 2011. p. 704-707. 6293729 https://doi.org/10.1109/ULTSYM.2011.0171
Li, Qian ; Qin, Yexian ; Ingram, Pier ; Witte, Russell S ; Wang, Zhaohui. / Ultrasound current source density imaging using a clinical intracardiac catheter. IEEE International Ultrasonics Symposium, IUS. 2011. pp. 704-707
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