Ultrasound current source density imaging using a clinical intracardiac catheter

Qian Li, Yexian Qin, Pier Ingram, Russell Witte, Zhaohui Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Radiofrequency catheter ablation for treatment of cardiac arrhythmia requires pre-surgical mapping of the heart's activation wave. However, modern cardiac mapping systems continue to suffer from significant limitations. We have proposed Ultrasound Current Source Density Imaging (UCSDI) as a new modality to map reentry currents in the heart. In this study, we focus on interfacing UCSDI with a clinical intra-cardiac catheter - a key step towards translating UCSDI to the clinic for guiding cardiac ablation therapy. Sensitivity of UCSDI combined with the catheter was tested in a tissue mimicking phantom and fresh excised porcine hear tissue. Effect of the recoding distance on the detection of UCSDI was also investigated. Sensitivity of UCSDI with catheter was 4.7 μV/mA (R 2 = 0.999) in cylindrical gel (0.9% NaCl), and 3.2 μV/mA (R 2 = 0.92) in porcine heart tissue. The AE signal was detectable more than 25 mm away from the source in cylindrical gel (0.9% NaCl).

Original languageEnglish (US)
Title of host publication2011 IEEE International Ultrasonics Symposium, IUS 2011
Pages704-707
Number of pages4
DOIs
StatePublished - Dec 1 2011
Event2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States
Duration: Oct 18 2011Oct 21 2011

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2011 IEEE International Ultrasonics Symposium, IUS 2011
CountryUnited States
CityOrlando, FL
Period10/18/1110/21/11

Keywords

  • ECG, EKG, multi-electrode recording
  • acoustoelectric effect
  • cardiac arrhythmia
  • catheter ablation

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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  • Cite this

    Li, Q., Qin, Y., Ingram, P., Witte, R., & Wang, Z. (2011). Ultrasound current source density imaging using a clinical intracardiac catheter. In 2011 IEEE International Ultrasonics Symposium, IUS 2011 (pp. 704-707). [6293729] (IEEE International Ultrasonics Symposium, IUS). https://doi.org/10.1109/ULTSYM.2011.0171