Ultrasound-mediated therapies using receptor-targeted nanodroplets

P. Schumann, R. Labell, K. Penrose, A. Kerschen, E. Unger, T. Matsunaga, R. Zutshi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Angiogenic vessels at tumor sites are leaky and allow particles less than 400 nm to pass through. We have developed targeted nanodroplets that are less than 400 nm in size and are capable of encapsulating drug molecules which can be released at the tumor site upon insonation. These nanodroplets are targeted to the α 6β 1 receptor, which is upregulated in prostate cancer.

Original languageEnglish (US)
Title of host publicationTHERAPEUTIC ULTRASOUND
Subtitle of host publication5th International Symposium on Therapeutic Ultrasound
Pages525-527
Number of pages3
DOIs
StatePublished - May 8 2006
Externally publishedYes
EventTHERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound - Boston, MA, United States
Duration: Oct 27 2005Oct 29 2005

Publication series

NameAIP Conference Proceedings
Volume829
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

OtherTHERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound
CountryUnited States
CityBoston, MA
Period10/27/0510/29/05

Keywords

  • Nanodroplets
  • Paclitaxel
  • Perfluorocarbon
  • Targeted delivery

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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  • Cite this

    Schumann, P., Labell, R., Penrose, K., Kerschen, A., Unger, E., Matsunaga, T., & Zutshi, R. (2006). Ultrasound-mediated therapies using receptor-targeted nanodroplets. In THERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound (pp. 525-527). (AIP Conference Proceedings; Vol. 829). https://doi.org/10.1063/1.2205529