TY - JOUR
T1 - Umbilical cord tissue mesenchymal stem cells
T2 - Characterization and clinical applications
AU - Harris, David T.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Umbilical cord tissue (CT) can provide a virtually unlimited source of multipotent mesenchymal stem cells (MSC) that can potentially be used in a variety of regenerative medicine and tissue engineering applications. Cord tissue segments can be frozen and preserved in liquid nitrogen dewars for prolonged periods of time, having been frozen in time at the peak of biological activity. CT stem cells are capable of giving rise to various mesenchymal and non-mesenchymal cell lineages including bone, cartilage, fat and neurons. Thus, CT stem cells are candidates to develop stem cell-based therapies for a wide variety of diseases including cardiovascular, ophthalmic, orthopedic and neurological applications. CT is currently being used in several regenerative medicine clinical studies, examples of which include treatment of graftversus-host disease and non-healing bone fractures. CT represents an additional source of stem cells that have both immediate and future applications for the individual donor.
AB - Umbilical cord tissue (CT) can provide a virtually unlimited source of multipotent mesenchymal stem cells (MSC) that can potentially be used in a variety of regenerative medicine and tissue engineering applications. Cord tissue segments can be frozen and preserved in liquid nitrogen dewars for prolonged periods of time, having been frozen in time at the peak of biological activity. CT stem cells are capable of giving rise to various mesenchymal and non-mesenchymal cell lineages including bone, cartilage, fat and neurons. Thus, CT stem cells are candidates to develop stem cell-based therapies for a wide variety of diseases including cardiovascular, ophthalmic, orthopedic and neurological applications. CT is currently being used in several regenerative medicine clinical studies, examples of which include treatment of graftversus-host disease and non-healing bone fractures. CT represents an additional source of stem cells that have both immediate and future applications for the individual donor.
KW - Cord tissue
KW - Mesenchymal stem cells
KW - Regenerative medicine
KW - Stem cells
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84888194005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888194005&partnerID=8YFLogxK
U2 - 10.2174/1574888X11308050006
DO - 10.2174/1574888X11308050006
M3 - Article
C2 - 23895058
AN - SCOPUS:84888194005
VL - 8
SP - 394
EP - 399
JO - Current Stem Cell Research and Therapy
JF - Current Stem Cell Research and Therapy
SN - 1574-888X
IS - 5
ER -