Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials

Geetanjali Saini, Keerthi Gogineni, Rick A. Kittles, Ritu Aneja

Research output: Contribution to journalReview articlepeer-review

Abstract

Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity.

Original languageEnglish (US)
Pages (from-to)605-611
Number of pages7
JournalBreast Cancer Research and Treatment
Volume187
Issue number3
DOIs
StatePublished - Jun 2021
Externally publishedYes

Keywords

  • African Americans
  • Ancestry informative markers
  • Oncology trials
  • Race/ethnicity classification

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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