Unilateral sporadic retinoblastoma presenting as acute secondary glaucoma with intraocular inflammation

Theresa R. Kramer, Todd M. Watanabe, Joseph M. Miller, Matthew W. Wilson, Richard R. Ober

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a case of unilateral sporadic retinoblastoma presenting as intraocular inflammation and secondary acute glaucoma in a six-year-old boy. Fine-needle aspiration biopsy (FNAB) of the anterior chamber was needed to confirm the diagnosis as both B-scan ultrasonography and computerized tomography (CT) revealed no intraocular mass or calcifications. Enucleation was performed. Histopathology showed a diffuse infiltrating retinoblastoma with involvement of the trabecular meshwork and Schlemm's canal. Because of the extensive duration of symptoms, the identification of tumor cells in Schlemm's canal/collector channels indicating possible extraocular extension, the patient received prophylactic chemotherapy. The patient has had no recurrence 24 months following treatment.

Original languageEnglish (US)
Pages (from-to)201-207
Number of pages7
JournalClinical and Surgical Ophthalmology
Volume26
Issue number6
StatePublished - Jun 2008
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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