Unloading the right ventricle in the crest syndrome variant of progressive systemic sclerosis (scleroderma)

D. Morrison, S. Goldman, F. P. Alepa

Research output: Contribution to journalArticle

2 Scopus citations


A patient with severe pulmonary hypertension secondary to the CREST syndrome variant of scleroderma is described. Acute reductions in both pulmonary artery pressure and total pulmonary resistance were seen with nifedipine and oxygen administration. Reductions in resistance were maintained for over one month with this combination. These results raise the possibility that some of the pulmonary hypertension seen in this condition is reversible.

Original languageEnglish (US)
Pages (from-to)49-53
Number of pages5
JournalClinical cardiology
Issue number1
StatePublished - Jan 1984



  • nifedipine
  • pulmonary hypertension
  • right ventricle
  • scleroderma

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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