US pharmacists' effect as team members on patient care: Systematic review and meta-analyses

Marie A. Chisholm-Burns, Jeannie K Lee, Christina A. Spivey, Marion K Slack, Richard N. Herrier, Elizabeth A Hall-Lipsy, Joshua Graff Zivin, Ivo L Abraham, John Palmer, Jennifer R. Martin, Sandra S. Kramer, Timothy Wunz

Research output: Contribution to journalArticle

459 Citations (Scopus)

Abstract

Background: One approach postulated to improve the provision of health care is effective utilization of team-based care including pharmacists. Objective: The objective of this study was to conduct a comprehensive systematic review with focused meta-analyses to examine the effects of pharmacist-provided direct patient care on therapeutic, safety, and humanistic outcomes. Methods: The following databases were searched from inception to January 2009: NLM PubMed; Ovid/MEDLINE; ABI/INFORM; Health Business Fulltext Elite; Academic Search Complete; International Pharmaceutical Abstracts; PsycINFO; Cochrane Database of Systematic Reviews; National Guideline Clearinghouse; Database of Abstracts of Reviews of Effects; ClinicalTrials.gov; LexisNexis Academic Universe; and Google Scholar. Studies selected included those reporting pharmacist-provided care, comparison groups, and patient-related outcomes. Of these, 56,573 citations were considered. Data were extracted by multidisciplinary study review teams. Variables examined included study characteristics, pharmacists' interventions/services, patient characteristics, and study outcomes. Data for meta-analyses were extracted from randomized controlled trials meeting meta-analysis criteria. Results: A total of 298 studies were included. Favorable results were found in therapeutic and safety outcomes, and meta-analyses conducted for hemoglobin A1c, LDL cholesterol, blood pressure, and adverse drug events were significant (P < 0.05), favoring pharmacists' direct patient care over comparative services. Results for humanistic outcomes were favorable with variability. Medication adherence, patient knowledge, and quality of life-general health meta-analyses were significant (P < 0.05), favoring pharmacists' direct patient care. Conclusions: Pharmacist-provided direct patient care has favorable effects across various patient outcomes, health care settings, and disease states. Incorporating pharmacists as health care team members in direct patient care is a viable solution to help improve US health care.

Original languageEnglish (US)
Pages (from-to)923-933
Number of pages11
JournalMedical Care
Volume48
Issue number10
DOIs
StatePublished - 2010

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Pharmacists
Meta-Analysis
Patient Care
Databases
Delivery of Health Care
Safety
Patient Care Team
Medication Adherence
Health
Drug-Related Side Effects and Adverse Reactions
PubMed
MEDLINE
LDL Cholesterol
Hemoglobins
Randomized Controlled Trials
Quality of Life
Outcome Assessment (Health Care)
Guidelines
Blood Pressure
Therapeutics

Keywords

  • direct patient care
  • meta-analysis
  • pharmacists
  • systematic review

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

Cite this

US pharmacists' effect as team members on patient care : Systematic review and meta-analyses. / Chisholm-Burns, Marie A.; Lee, Jeannie K; Spivey, Christina A.; Slack, Marion K; Herrier, Richard N.; Hall-Lipsy, Elizabeth A; Graff Zivin, Joshua; Abraham, Ivo L; Palmer, John; Martin, Jennifer R.; Kramer, Sandra S.; Wunz, Timothy.

In: Medical Care, Vol. 48, No. 10, 2010, p. 923-933.

Research output: Contribution to journalArticle

Chisholm-Burns, MA, Lee, JK, Spivey, CA, Slack, MK, Herrier, RN, Hall-Lipsy, EA, Graff Zivin, J, Abraham, IL, Palmer, J, Martin, JR, Kramer, SS & Wunz, T 2010, 'US pharmacists' effect as team members on patient care: Systematic review and meta-analyses', Medical Care, vol. 48, no. 10, pp. 923-933. https://doi.org/10.1097/MLR.0b013e3181e57962
Chisholm-Burns, Marie A. ; Lee, Jeannie K ; Spivey, Christina A. ; Slack, Marion K ; Herrier, Richard N. ; Hall-Lipsy, Elizabeth A ; Graff Zivin, Joshua ; Abraham, Ivo L ; Palmer, John ; Martin, Jennifer R. ; Kramer, Sandra S. ; Wunz, Timothy. / US pharmacists' effect as team members on patient care : Systematic review and meta-analyses. In: Medical Care. 2010 ; Vol. 48, No. 10. pp. 923-933.
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