Utilize conjugated melanotropins for the earlier diagnosis and treatment of melanoma

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Peptides serve as effective drugs and contrast agents in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this we have been developing new methods to create 'tailor-made' peptides and peptide mimetics with improved pharmacological and physical properties. In this work we introduce novel peptide and small molecule conjugated molecules for earlier diagnosis and treatment of melanoma.

Original languageEnglish (US)
Pages (from-to)188-193
Number of pages6
JournalEuropean Journal of Pharmacology
Volume660
Issue number1
DOIs
StatePublished - Jun 11 2011

Fingerprint

Melanocyte-Stimulating Hormones
Early Diagnosis
Melanoma
Peptides
Pharmaceutical Preparations
Contrast Media
Pharmacology

Keywords

  • Human melanocortin receptors
  • Melanoma
  • Melanotropin
  • MTII
  • Selective ligands for MC receptors
  • THIQ

ASJC Scopus subject areas

  • Pharmacology

Cite this

Utilize conjugated melanotropins for the earlier diagnosis and treatment of melanoma. / Cai, Minying; Liu, Zhonglin; Qu, Hongchang; Fan, Helen; Zheng, Zhiping; Hruby, Victor J.

In: European Journal of Pharmacology, Vol. 660, No. 1, 11.06.2011, p. 188-193.

Research output: Contribution to journalArticle

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