Uvaretin, a new antitumor agent from Uvaria acuminata (annonaceae)

Jack R Cole, Sterling J. Torrance, Richard M. Wiedhopf, Satish K. Arora, Robert B. Bates

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The chloroform extract of Uvaria acuminata Oliv. has shown inhibitory activity against the P-388 lymphocytic leukemia test system of the National Cancer Institute. The major constituent of this extract was identified as the new 3′-benzyldihydrochalcone uvaretin, 1-[2,4-dihydroxy-3-(2-hydroxybenzyl)-6-methoxyphenyl]-3-phenyl-1-propanone (C23H22O5). The structure was proven by x-ray crystallography and other methods.

Original languageEnglish (US)
Pages (from-to)1852-1855
Number of pages4
JournalJournal of Organic Chemistry
Volume41
Issue number10
StatePublished - 1976

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Antineoplastic Agents
Crystallography
Chloroform
X rays
uvaretin

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Cole, J. R., Torrance, S. J., Wiedhopf, R. M., Arora, S. K., & Bates, R. B. (1976). Uvaretin, a new antitumor agent from Uvaria acuminata (annonaceae). Journal of Organic Chemistry, 41(10), 1852-1855.

Uvaretin, a new antitumor agent from Uvaria acuminata (annonaceae). / Cole, Jack R; Torrance, Sterling J.; Wiedhopf, Richard M.; Arora, Satish K.; Bates, Robert B.

In: Journal of Organic Chemistry, Vol. 41, No. 10, 1976, p. 1852-1855.

Research output: Contribution to journalArticle

Cole, JR, Torrance, SJ, Wiedhopf, RM, Arora, SK & Bates, RB 1976, 'Uvaretin, a new antitumor agent from Uvaria acuminata (annonaceae)', Journal of Organic Chemistry, vol. 41, no. 10, pp. 1852-1855.
Cole JR, Torrance SJ, Wiedhopf RM, Arora SK, Bates RB. Uvaretin, a new antitumor agent from Uvaria acuminata (annonaceae). Journal of Organic Chemistry. 1976;41(10):1852-1855.
Cole, Jack R ; Torrance, Sterling J. ; Wiedhopf, Richard M. ; Arora, Satish K. ; Bates, Robert B. / Uvaretin, a new antitumor agent from Uvaria acuminata (annonaceae). In: Journal of Organic Chemistry. 1976 ; Vol. 41, No. 10. pp. 1852-1855.
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