Value of serum 125Ca levels: Does the result preclude second look?

Mark E. Potter, Mark Moradi, Alexander C W To, Kenneth D Hatch, Hugh M. Shingleton

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Forty-five women with known histories of ovarian cancer underwent reoperative surgery. Thirty-seven patients underwent routine second-look laparotomy and eight patients were reexplored with clinical evidence of disease with the intent of re-resection. Preoperative CA 125 levels were obtained. Evaluation as to the predictive value of the CA 125 level and operative findings show a positive predictive value of 100% and a negative predictive value of 54%. Twenty of the forty-five patients had gross disease present on reoperation. Twenty patients were found to have persistent disease at reoperation. Twenty-five percent of patients with CA 125 levels less than or equal to 35 U/ml and 37% of these with CA 125 levels greater than 35 U/ml were resectable to no gross disease at the completion of the reoperation. CA 125 levels greater than or less than 35 U/ml were not predictive of the potential for re-resectability of the tumor.

Original languageEnglish (US)
Pages (from-to)201-203
Number of pages3
JournalGynecologic Oncology
Volume33
Issue number2
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Reoperation
Serum
Ovarian Neoplasms
Laparotomy
Neoplasms

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Value of serum 125Ca levels : Does the result preclude second look? / Potter, Mark E.; Moradi, Mark; To, Alexander C W; Hatch, Kenneth D; Shingleton, Hugh M.

In: Gynecologic Oncology, Vol. 33, No. 2, 1989, p. 201-203.

Research output: Contribution to journalArticle

Potter, Mark E. ; Moradi, Mark ; To, Alexander C W ; Hatch, Kenneth D ; Shingleton, Hugh M. / Value of serum 125Ca levels : Does the result preclude second look?. In: Gynecologic Oncology. 1989 ; Vol. 33, No. 2. pp. 201-203.
@article{c05fb6f9cd6241b0a2deb6e7fa775274,
title = "Value of serum 125Ca levels: Does the result preclude second look?",
abstract = "Forty-five women with known histories of ovarian cancer underwent reoperative surgery. Thirty-seven patients underwent routine second-look laparotomy and eight patients were reexplored with clinical evidence of disease with the intent of re-resection. Preoperative CA 125 levels were obtained. Evaluation as to the predictive value of the CA 125 level and operative findings show a positive predictive value of 100{\%} and a negative predictive value of 54{\%}. Twenty of the forty-five patients had gross disease present on reoperation. Twenty patients were found to have persistent disease at reoperation. Twenty-five percent of patients with CA 125 levels less than or equal to 35 U/ml and 37{\%} of these with CA 125 levels greater than 35 U/ml were resectable to no gross disease at the completion of the reoperation. CA 125 levels greater than or less than 35 U/ml were not predictive of the potential for re-resectability of the tumor.",
author = "Potter, {Mark E.} and Mark Moradi and To, {Alexander C W} and Hatch, {Kenneth D} and Shingleton, {Hugh M.}",
year = "1989",
doi = "10.1016/0090-8258(89)90552-0",
language = "English (US)",
volume = "33",
pages = "201--203",
journal = "Gynecologic Oncology",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Value of serum 125Ca levels

T2 - Does the result preclude second look?

AU - Potter, Mark E.

AU - Moradi, Mark

AU - To, Alexander C W

AU - Hatch, Kenneth D

AU - Shingleton, Hugh M.

PY - 1989

Y1 - 1989

N2 - Forty-five women with known histories of ovarian cancer underwent reoperative surgery. Thirty-seven patients underwent routine second-look laparotomy and eight patients were reexplored with clinical evidence of disease with the intent of re-resection. Preoperative CA 125 levels were obtained. Evaluation as to the predictive value of the CA 125 level and operative findings show a positive predictive value of 100% and a negative predictive value of 54%. Twenty of the forty-five patients had gross disease present on reoperation. Twenty patients were found to have persistent disease at reoperation. Twenty-five percent of patients with CA 125 levels less than or equal to 35 U/ml and 37% of these with CA 125 levels greater than 35 U/ml were resectable to no gross disease at the completion of the reoperation. CA 125 levels greater than or less than 35 U/ml were not predictive of the potential for re-resectability of the tumor.

AB - Forty-five women with known histories of ovarian cancer underwent reoperative surgery. Thirty-seven patients underwent routine second-look laparotomy and eight patients were reexplored with clinical evidence of disease with the intent of re-resection. Preoperative CA 125 levels were obtained. Evaluation as to the predictive value of the CA 125 level and operative findings show a positive predictive value of 100% and a negative predictive value of 54%. Twenty of the forty-five patients had gross disease present on reoperation. Twenty patients were found to have persistent disease at reoperation. Twenty-five percent of patients with CA 125 levels less than or equal to 35 U/ml and 37% of these with CA 125 levels greater than 35 U/ml were resectable to no gross disease at the completion of the reoperation. CA 125 levels greater than or less than 35 U/ml were not predictive of the potential for re-resectability of the tumor.

UR - http://www.scopus.com/inward/record.url?scp=0024478083&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024478083&partnerID=8YFLogxK

U2 - 10.1016/0090-8258(89)90552-0

DO - 10.1016/0090-8258(89)90552-0

M3 - Article

C2 - 2703182

AN - SCOPUS:0024478083

VL - 33

SP - 201

EP - 203

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 2

ER -