Vaporising phase change ultrasound contrast agent in microvascular confinement

Shengtao Lin, Ge Zhang, Chee Hau Leow, Terry O Matsunaga, Meng Xing Tang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Citations (Scopus)

Abstract

The sub-micron perfluorocarbon-based phase change contrast agents (PCCAs) have shown great potential for imaging both microvasculature and tumour microenvironment. However the effect of geometrical confinement on the acoustic vaporisation has not been explored. We report the investigation of the difference in PCCA-produced contrast increase after activation with and without a microvessel confinement using in vitro experiment phantom. The results demonstrated that the acoustic vaporisation of PCCAs in the 200-micron cellulose tube was significantly different from that in the open environment, with contrast enhancement suppressed by up to several fold.

Original languageEnglish (US)
Title of host publication2016 IEEE International Ultrasonics Symposium, IUS 2016
PublisherIEEE Computer Society
Volume2016-November
ISBN (Electronic)9781467398978
DOIs
StatePublished - Nov 1 2016
Event2016 IEEE International Ultrasonics Symposium, IUS 2016 - Tours, France
Duration: Sep 18 2016Sep 21 2016

Other

Other2016 IEEE International Ultrasonics Symposium, IUS 2016
CountryFrance
CityTours
Period9/18/169/21/16

Fingerprint

vaporizing
acoustics
cellulose
tumors
activation
tubes
augmentation

Keywords

  • acoustic vaporisation
  • microbubbles
  • microvessel
  • nanodroplets
  • phase change contrast agent
  • ultrasound

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Lin, S., Zhang, G., Leow, C. H., Matsunaga, T. O., & Tang, M. X. (2016). Vaporising phase change ultrasound contrast agent in microvascular confinement. In 2016 IEEE International Ultrasonics Symposium, IUS 2016 (Vol. 2016-November). [7728724] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2016.7728724

Vaporising phase change ultrasound contrast agent in microvascular confinement. / Lin, Shengtao; Zhang, Ge; Leow, Chee Hau; Matsunaga, Terry O; Tang, Meng Xing.

2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November IEEE Computer Society, 2016. 7728724.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lin, S, Zhang, G, Leow, CH, Matsunaga, TO & Tang, MX 2016, Vaporising phase change ultrasound contrast agent in microvascular confinement. in 2016 IEEE International Ultrasonics Symposium, IUS 2016. vol. 2016-November, 7728724, IEEE Computer Society, 2016 IEEE International Ultrasonics Symposium, IUS 2016, Tours, France, 9/18/16. https://doi.org/10.1109/ULTSYM.2016.7728724
Lin S, Zhang G, Leow CH, Matsunaga TO, Tang MX. Vaporising phase change ultrasound contrast agent in microvascular confinement. In 2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November. IEEE Computer Society. 2016. 7728724 https://doi.org/10.1109/ULTSYM.2016.7728724
Lin, Shengtao ; Zhang, Ge ; Leow, Chee Hau ; Matsunaga, Terry O ; Tang, Meng Xing. / Vaporising phase change ultrasound contrast agent in microvascular confinement. 2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November IEEE Computer Society, 2016.
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