Variability of heating patterns in animals by magnetic induction hyperthermia

F. Kristian Storm, Douglas A. Christensen, Arthur J. Olch, Allan W. Silberman, Denise J. Roe, William H. Harrison, Robert S. Elliott, Donald L. Morton

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Abstract

In a test of electromagnetic induction hyperthermia to deep viscera of a live dog model, we found that heating was not uniform to any depth, but was quite variable. In general, there was a thermal gradient between peripheral and central portions of the transposed spleen of about 1°C. Though heat generation within the abdomen was not uniform, its temperature pattern in the alive animal resulted in significant heating of that part of the organ that had been surgically placed at the center of the animal. This heating could not be explained by perfusion with regionally heated core blood. Our results indicate that extensive investigations in living systems and complex dynamic phantoms will be necessary before individual patient response can be predicted.

Original languageEnglish (US)
Pages (from-to)82-88
Number of pages7
JournalJournal of Surgical Oncology
Volume29
Issue number2
DOIs
StatePublished - Jun 1985
Externally publishedYes

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Keywords

  • animal model
  • hyperthermia
  • magnetic induction

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Storm, F. K., Christensen, D. A., Olch, A. J., Silberman, A. W., Roe, D. J., Harrison, W. H., Elliott, R. S., & Morton, D. L. (1985). Variability of heating patterns in animals by magnetic induction hyperthermia. Journal of Surgical Oncology, 29(2), 82-88. https://doi.org/10.1002/jso.2930290204